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Respiratory Aspiration clinical trials

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NCT ID: NCT04786184 Completed - COPD Clinical Trials

Capnography-Assisted Learned Monitored (CALM) Breathing Therapy for COPD

CALM
Start date: November 30, 2021
Phase: N/A
Study type: Interventional

This pilot study is part of a phased approach to refine, optimize, and test the feasibility of CALM Breathing. Preliminary participant feedback from the Capnography-Assisted Respiratory Therapy (CART) study was applied to adapt and design CALM Breathing (including its dose, schedule, delivery, and home program). This pilot builds on initial lessons learned and identifies intervention areas still needing greater development to assure the success of a future large trial, targeting a subpopulation at risk, that is, those with COPD and anxiety sensitivity.

NCT ID: NCT04783155 Recruiting - Clinical trials for Post-Lung Transplantation Bronchiectasis

Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant

Start date: May 10, 2021
Phase: N/A
Study type: Interventional

The purpose of this research is to study the effect of training the inspiratory muscles (i.e. the muscle that allow you to breath-in) on exercise capacity, quality of life, and short-term clinical outcomes in patients post lung transplant.

NCT ID: NCT04780815 Completed - Healthy Volunteers Clinical Trials

An Exploratory PET-study of Deposition, Disposition and Brain Uptake of [11C]Nicotine After Inhalation of 2 Nicotine Formulations Via the myBluTM E-cigarette in Smokers

Start date: March 16, 2020
Phase: N/A
Study type: Interventional

This is a single-center, exploratory positron emission tomography (PET) study of deposition, disposition and brain uptake [11C]nicotine when given to smokers as two different formulations via mybluTM e-cigarette system.

NCT ID: NCT04776122 Completed - Breathing, Mouth Clinical Trials

Usability of a Breathing-CBT Platform (CBT = Cognitive Behavioural Therapy)

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The study will examine the usability of a breathing platform in the home environment. It will be a randomized, open-label crossover study of 10 participants who will complete the CBT and breathing components in their home, prior to sleeping. Usability will be measured by scores assigned by participants. Qualitative feedback and compliance information will also be collected.

NCT ID: NCT04772794 Recruiting - Immune System Clinical Trials

Immunologic Effect of Fraction of Inspired Oxygen

Start date: January 13, 2020
Phase: N/A
Study type: Interventional

During anesthesia and surgery, oxygen is routinely administered to all patients. Inspired oxygen concentrations, however, vary between 30% - 100% and oxygen is often administered in a seemingly random manner.

NCT ID: NCT04771598 Completed - Covid19 Clinical Trials

EVALUATING THE EFFICIENCY OF BREATHING EXERCISES PERFORMED BY POST-COVID TELEMEDICINE: Randomized Controlled Study

Start date: February 25, 2021
Phase: N/A
Study type: Interventional

As an important non-drug intervention in the treatment of respiratory tract diseases, respiratory rehabilitation training is increasingly accepted in clinical practice. The purpose of pulmonary rehabilitation is not only to improve the physical and mental conditions of the patient, but also to help the patient return to the family and society more quickly. In light of the widely documented lung injuries associated with COVID-19, concerns are raised regarding the assessment of lung injury in discharged patients. As an important non-drug intervention in the treatment of respiratory diseases, respiratory rehabilitation training is increasingly being accepted in clinical practice The purpose of pulmonary rehabilitation is not only to improve the physical and mental conditions of the patient, but also to help the patient return to the family and society more quickly. The aim of the study; It is aimed to evaluate the efficiency of breathing exercise in individuals with COVID-19.

NCT ID: NCT04754490 Suspended - COPD Clinical Trials

Exploring Breathing Patterns

EPISODE
Start date: March 1, 2019
Phase:
Study type: Observational

Study Title Exploring patterns of speech and breathing to indicate the presence of obstructive respiratory disease. Study Design Prospective Case Control Study Study Participants Participants will be patients attending the respiratory physiology clinic at the Cardiopulmonary Unit, Prince Charles Hospital for an assessment of their lung function. In addition a cohort of control participants without obstructive respiratory disease will be recruited with the assistance of the British Lung Foundation charity. Planned Size of Sample (if applicable) We have received funding for 52 ½ day sessions and we plan to recruit on average 2 participants per session. As such we aim to recruit a minimum of 100 participants. In addition we are working with the British Lung Foundation to recruit a smaller Cohort of control participants and aim to recruit a minimum of 25 control participants. Planned Study Period Jan 2019 - Aug 2019 Research Aim(s) This primary objective of this novel study it to create an anonymised database of speech patterns of patients with chronic respiratory disease and healthy aged matched controls for comparison with lung function and medical history. The primary aims are to: - Collect breathing patterns from individuals under a range of talking modalities - Understand how easy it is to gather short speech recordings - Explore the preferences of patients to be recorded talking

NCT ID: NCT04746040 Active, not recruiting - Asthma Clinical Trials

A Bioequivalence Study Between Fluticasone Propionate 250 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 250/50 Inhalation Powder/GSK in Healthy Volunteers

Start date: January 18, 2021
Phase: Phase 1
Study type: Interventional

Bioequivalence study between two inhaler products of fixed dose combination of fluticasone propionate and salmeterol xinafoate inhalation powder

NCT ID: NCT04734795 Completed - Asthma Clinical Trials

The Prevalence of Dysfunctional Breathing in Children and Adolescents With Asthma

Start date: February 5, 2021
Phase:
Study type: Observational

The purpose of the study is to investigate the prevalence of dysfunctional breathing in children and adolescents with asthma in a hospital outpatient clinic. Participants are invited to take the Nijmegen Questionnaire and the Asthma Control Questionnaire. The prevalence of dysfunctional breathing defined as NQ score >= 23 is calculated, and demographics are compared between children with and without dysfunctional breathing.

NCT ID: NCT04734509 Completed - Clinical trials for Nitrous Oxide Inhalation Sedation

Comparison of the Silhouette and Porter Brown Systems Used in Inhalation Sedation

Start date: February 21, 2019
Phase: N/A
Study type: Interventional

This is a randomised non-blinded controlled clinical trial, which involves the measurement of efficiency and acceptability of the Silhouette Mask system and compares it with the Porter Brown Mask system used for Inhalation Sedation in children having dental treatment at the Leeds Dental Institute. All eligible participants will be introduced to both masks (Porter Brown and Silhouette) in the assessment session prior to their first treatment session. Then participants will be randomly allocated to undergo treatment under nitrous oxide-oxygen inhalation sedation using either the Porter Brown or the Silhouette System. The efficiency and acceptability will be measured by a feedback questionnaire at the end of the treatment session and the scavenging efficiency will be measured by a diffusion pen which will measure the levels of nitrous oxide in the dentist's environment