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Respiratory Aspiration clinical trials

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NCT ID: NCT03142022 Recruiting - Clinical trials for Lung Transplantation

Sleep-disordered Breathing After Solid Organ Transplantation

Start date: November 2014
Phase:
Study type: Observational

Sleep-disordered breathing (SDB) describes a group of disorders in which partial or complete cessation of breathing occurs many times throughout the night, resulting in daytime sleepiness or fatigue that interferes with a person's ability to function and reduces quality of life. Transplantation has become an important treatment modality for end-stage organ failure. Transplant recipients are now living longer and, hence, develop chronic adverse medical conditions. Furthermore, transplantation is associated with weight gain. Despite the high prevalence of poor sleep and cardiovascular conditions among transplant patients, SDB is not well studied in these patients.

NCT ID: NCT03108430 Recruiting - Risk Factor Clinical Trials

Study of Risk Factors for Developing Inhalation Pneumonia After Inhalation

PrevAsPI-Obs
Start date: August 22, 2016
Phase: N/A
Study type: Observational

Inhalation pneumonia (PI) is common in clinical practice but is rarely studied. For example, there are no data on the incidence of pneumonia after inhalation and risk factors or protective factors to develop one since it is known that anyone who inhaled does not necessarily develop an IP. There is no data on the benefit of treating inhalation by antibiotic therapy pre-emptively although this practice is common. In this context, this observational study wishes to take stock of the situation on the subject in order to determine what actions to implement to prevent IP.

NCT ID: NCT03080662 Recruiting - Clinical trials for Inspiratory Muscle Training

Impact of Inspiratory Muscle Training on Daily Physical Activity (INAF)

Start date: January 22, 2015
Phase: N/A
Study type: Interventional

The impact of the reduction of daily physical activity (DPA) in patients with COPD (chronic obstructive pulmonary disease) is a highly studied area, due to its impact on the quality of life and the clinical evolution of the disease . This fact has multifactorial components: its function is naturally diminished with time, and its effects on the loss of physical condition (decondition). However, dynamic hyperinflation and respiratory muscular dysfunction, especially in patients with more symptomatology, have been identified as those that have the most relevant factors that impact on daily physical activity Due to the detrimental effects of the pulmonary hyperinflation, the diaphragm is flatter and shorter, being in a position of mechanical disadvantage. This contributes to a reduced effort capacity and increase in the dyspnea of patients during daily activities. Resistance training improves their exercise capacity and reduces dyspnea, however it does not improve inspiratory muscle strength. It is for this reason, that specific training of the inspiratory muscles, offers special interest in patients with decreased inspiratory muscle strength and pulmonary hyperinflation.

NCT ID: NCT03040596 Recruiting - Vocal Fold Nodules Clinical Trials

The Effect of Inhaled Corticosteroids on Vocal Fold Nodules in Children

Start date: March 1, 2017
Phase: Phase 1
Study type: Interventional

Voice disorders are the most common communication disorder across the lifespan and vocal fold nodules are the most frequent pathology affecting voice in children. The goal of the present study is to determine the safety, feasibility, and efficacy of a short-course of inhaled corticosteroids in addition to standard voice therapy for treating vocal fold nodules.

NCT ID: NCT02906267 Recruiting - Clinical trials for Positive-Pressure Respiration

Ultrasonographic Comparison of Gastric Volume After Three Modes of Positive Facemask During Induction of Anaesthesia

UGV
Start date: December 2016
Phase: N/A
Study type: Interventional

This study is designed to evaluate the occurrence of gastric insufflation and the critical volume of the stomach after three different modes of positive pressure ventilation during induction (Manual-controlled, volume-controlled and pressure-controlled ventilation)

NCT ID: NCT02877745 Recruiting - Clinical trials for Coronary Artery Disease

Sleep-disordered Breathing and Perioperative Atrial Fibrillation in Cardiac Surgery

CONSIDER-AF
Start date: July 2016
Phase:
Study type: Observational

In patients undergoing elective coronary artery bypass grafting (CABG) surgery, coronary artery disease, sleep-disordered breathing (SDB), atrial fibrillation (AF) perioperative atrial fibrillation and complications will be assessed. The primary objective is to determine, whether SDB patients have a higher rate of Major Adverse Cardiac and Cerebrovascular Events (MACCE) within 30 days after surgery compared to those without SDB.

NCT ID: NCT02833168 Recruiting - Clinical trials for Neuromuscular Disorders

Screening Questionnaire for Respiratory Muscle Weakness and Sleep-disordered Breathing in Neuromuscular Disorders

Start date: April 2016
Phase: N/A
Study type: Observational

It is the aim of this project to develop and validate a German language screening questionnaire for symptoms of respiratory muscle weakness and sleep-disordered breathing (SDB) in patients with neuromuscular disorders.

NCT ID: NCT02794935 Recruiting - Clinical trials for Chronic Heart Failure

The Effects of Inspiratory Muscle Training in Patients With Heart Failure and Obstructive Sleep Apnea Syndrome

Start date: June 2016
Phase: N/A
Study type: Interventional

This research aims to evaluate the effects of inspiratory muscle training (IMT) on apnea hypopnea index, sleepiness, sleep quality, cognitive function, motor task, executive function, quality of life, chemoreflex sensitivity and vagal modulation of heart rate in patients with heart failure and obstructive sleep apnea syndrome.

NCT ID: NCT02765295 Recruiting - Oxidative Stress Clinical Trials

Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis: A Randomized, Multi-center, Double-blind Study

HYBRID
Start date: June 1, 2016
Phase: N/A
Study type: Interventional

This is a multi-center, randomized, double-blind, parallel-group trial. After a 2-week run-in period, eligible patients will be, based on the randomization codes kept in sealed envelopes, randomly assigned to receive usual care (mucolytics and/or chest physiotherapy) plus oxygen inahaltion (1 hr daily for 12 consecutive months) or hydrogen inhalation (1 hr daily for 12 consecutive months) provided by the sponsor. At 3 months after the end-of-treatment, a follow-up visit will be scheduled for all patients.

NCT ID: NCT02722629 Recruiting - COPD Clinical Trials

Prevalence of Respiratory Aspiration in Patients With COPD

Start date: June 2016
Phase: N/A
Study type: Interventional

The aim of the study is to estimate the prevalence of respiratory aspiration in patients with COPD, in a tertiary hospital of Buenos Aires.