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Clinical Trial Summary

This study was planned to assess the concentration of antihypertensive drugs in the blood plasma in patients with controlled and uncontrolled arterial hypertension. Methods: it is planned to include patients with arterial hypertension taking 3 antihypertensive drugs (indapanide, lisinopril or valsartan, amlodipine). Based on the results of 24-hour blood pressure monitoring, the patients will be randomized into two groups: The first group - the patients with controlled AH; The second group - the patients with uncontrolled AH. Venous blood was taken in both groups of the patients in the morning before and 2 hours after taking drugs to assess the concentration of lisinopril, amlodipine, valsartan and indapamide. Concentation of assesed antihypertensive drugs will be compared in both groups.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05899920
Study type Interventional
Source Ryazan State Medical University
Contact Sergey V Seleznev, MD, PhD
Phone +79105749526
Email sv.seleznev@gmail.com
Status Recruiting
Phase N/A
Start date March 11, 2022
Completion date December 31, 2024

See also
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Completed NCT03243045 - Systemic Microvascular Function in Patients With Resistant Hypertension After Renal Sympathetic Denervation