Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study

Renal Cell Carcinoma Clinical Trial

Official title:

Comparison of Erector Spina and Quadratus Lumborum in Open Nephrectomy

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT05810571
• Other study ID #: KAEK / 12bl.01
• Status: Active, not recruiting
• Phase: N/A
• Start date: March 1, 2023
• Est. completion date: April 3, 2024

Study information

• Verified date: March 2023
• Source: Kocaeli University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block, and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continuous remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Description:

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continious remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 60
• Est. completion date: April 3, 2024
• Est. primary completion date: January 3, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• ASA 1-3

• open nephrectomy elective patients

• BMI<35

Exclusion Criteria:

• ASA 4-5-6

• Laparoscopic nephrectomy

• infection at the block side

• coagulation disorder

• BMI>35

Related Conditions & MeSH terms

• Carcinoma, Renal Cell
• Renal Cell Carcinoma

Intervention

Procedure:
• preoperative remifentanil consumption
continuous remifentanil infusion will applied for peroperative analgesia
• postopeartive controlled anlagesia with morphine
postoperative morphine patient controlled analgesia will be applied for postoperative analgesia

Locations

Country	Name	City	State
Turkey	Kocaeli University Medical Faculty	Kocaeli
Turkey	Kocaeli University School of Medicine	Kocaeli

Sponsors (1)

Lead Sponsor	Collaborator
Kocaeli University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	postoperative morphine consumption	amount of postoperative morphine use of the patient's	24 hour postoperatively
Secondary	peroperative remifentanil consumptions	amount of remifentanil use of the patient's	4 hour preoperatively
Secondary	numeric rating scale	numeric rating scores of the patient's postoepartively	24 hour postoperatively