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Significance of Immunohistochemical Expression of Survivin in Renal Cell Carcinoma

Renal Cell Carcinoma Clinical Trial

Official title:
A Retrospective Study

Clinical Trial Summary

detection of Survivin expression in renal cell carcinoma and correlate this expression to tumor grade and stage.

Clinical Trial Description

renal cell carcinoma is the third most prevalent malignant tumor of the genitourinary system. deregulation of apoptosis is involved in carcinogenesis by abnormally prolonged cell survival, facilitating accumulations of multiple mutations and augment resistance to immune-surveillance. Survivin is a member of inhibitor of Apoptosis Protein family (IAPs). it play a role in cell cycle regulation by inhibiting apiptosis. Survivin is over-expressed in many human neoplasms. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04873180
Study type Observational
Source Sohag University
Contact
Status Completed
Phase
Start date January 1, 2020
Completion date December 30, 2020
View Details
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