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Recurrence clinical trials

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NCT ID: NCT04415918 Not yet recruiting - Clinical trials for Clostridium Difficile Infection Recurrence

Bezlotoxumab Efficacy and Tolerability in Cancer Patient

Start date: July 1, 2020
Phase: Phase 4
Study type: Interventional

Investigation of efficacy and tolerability of bezlotoxumab in patients with cancer diagnosis in terms of preventing CDI recurrence.

NCT ID: NCT04404491 Not yet recruiting - Clinical trials for Esophageal Malignant Neoplasm, Local Recurrence

Clinical Control Study of Immunotherapy and Concurrent Chemoradiotherapy in Patients With Esophageal Cancer Recurrence

Start date: June 1, 2020
Phase: Phase 3
Study type: Interventional

Esophageal cancer is still a serious threat to human life and health. China in particular. Relapse and metastasis are important causes of treatment failure. Immunotherapy is a new treatment method, which can be used in combination with chemotherapy to improve the therapeutic effect. However, the role of immunotherapy combined with chemoradiotherapy in concurrent chemoradiotherapy of recurrent esophageal cancer has not been clearly studied. Our team will study it in detail. The purpose of this study was to compare and analyze the effect of Camrelizumab in concurrent chemoradiotherapy of locally recurrent esophageal cancer.

NCT ID: NCT04384237 Not yet recruiting - Rotated Teeth Clinical Trials

Er,Cr:YSGG Laser-aided Fiberotomy in the Prevention of the Lower Incisors Rotational Relapse

laser
Start date: March 2021
Phase: N/A
Study type: Interventional

To establish the effect of erbium, chromium,yttrium,scandium,gallium and garnet (Er,Cr: YSGG) laser-aided circumferential supracrestal fiberotomy compared to a conventional circumferential supracrestal fiberotomy group, after leveling and alignment during the first month after arch wire removal on the prevention of rotational relapse in lower incisors. Methods: Randomized clinical trial in 60 orthodontic patients with two to four lower incisors rotation between 30º-50º degrees before treatment.They are going to be assigned in two intervention groups, each group with 30 patients. One group are going to be treated with Er;Cr: YSGG laser -aided CSF and the other group with conventional circumferential supracrestal fiberotomy. After leveling and alignment each procedure will be performed and after one month healing the arch wire will be removed for a month and lower incisor relapse will be measured through cast models in a software. Periodontal parameters will be registered before and after procedures.The outcomes are going to be determined and compared between groups with corresponding statistical test and results will be analyzed

NCT ID: NCT04297085 Not yet recruiting - Clinical trials for Thromboembolic Venous Disease

Prospective Cohort Study on the Determinants of Venous THromboembolic Recurrence

BREIZH-Cohorte
Start date: April 2020
Phase: N/A
Study type: Interventional

The main objective of the BREIZH-Cohorte study is to determine the incidence of recurrent short, medium and long-term thromboembolic venous disease as well as risk factors for recurrence in two specific populations: patients under 50 years of age, men and women (5 year recurrence), as well as cancer patients (all ages) (1 year recurrence).

NCT ID: NCT04237740 Not yet recruiting - Clinical trials for Hepatocellular Carcinoma

Relenvatinib in the Tatment of Recurrence of Hepatocellular Carcinoma After Liver Transplantation

RRHCCLT
Start date: May 1, 2020
Phase: Phase 3
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of lenvatinib in the treatment of recurrence of hepatocellular carcinoma after liver transplantation.

NCT ID: NCT04227249 Not yet recruiting - Endometrial Cancer Clinical Trials

3 Year Recurrence Free Survival in Ultra-low-risk Endometrial Cancer

TREE PRO
Start date: April 2020
Phase:
Study type: Observational

To verify the safety of omission of lymph node dissection in ultra-low-risk endometrial cancer (KGOG criteria), we examine the survival of women with ultra-low-risk endometrial cancer who do not undergo lymph node dissection

NCT ID: NCT04190472 Not yet recruiting - Recurrence Clinical Trials

Intraoperative HPV Testing Evaluation

Start date: June 1, 2020
Phase:
Study type: Observational

High-grade intraepithelial lesion/cervical intraepithelial neoplasia grade 2-3 is a premalignant cervical lesion caused by persistent high-risk human papillomavirus infection. Human papillomavirus test is a very sensitive risk marker of cervical cancer and it has been incorporated in the follow-up after high-grade intraepithelial lesion treatment. Papillomavirus test performed intraoperatively could be a beneficial approach to anticipate treatment failure, allow for early management and consequently a reduction in costs. The aim of this study is to evaluate if the IOP-HPV test has non-inferior diagnostic utility of HSIL/CIN2-3 recurrence at 24 months as the HPV test performed 6 months after treatment.

NCT ID: NCT04155879 Not yet recruiting - Atrial Fibrillation Clinical Trials

Atrial Fibrillation Recurrence Following Cardioversion: the Role of Clinical Factors and Alpha Defensin Levels

Start date: November 2019
Phase: N/A
Study type: Interventional

Atrial fibrillation and inflammation are strongly correlated. The aim of this study is to evaluate whether inflammation markers (alpha Defensin) predict maintenance of sinus rhythm following cardioversion. A secondary aim is to evaluate the role of Colchicine, an anti-inflammatory medication, in reducing the recurrence rate of atrial fibrillation.

NCT ID: NCT04134793 Not yet recruiting - Atrial Fibrillation Clinical Trials

Correlation of Atrial Fibrillation Recurrence After Bipolar Radiofrequency Ablation With microRNA Expression

Start date: October 2019
Phase:
Study type: Observational

The recurrence rate of atrial fibrillation (AF) after bipolar radiofrequency ablation was about 30%. Besides the factors, left atrium diameter, the duration of AF, NT-proBNP, and ejection fraction(EF), some studies demonstrated that the specific microRNA expression (miRNA1, miRNA19,miRNA23, miRNA409 ) showed the significant change in AF patients compared with normal sinus patients, who underwent catheter ablation. Therefore, the correlation of atrial fibrillation recurrence and above-mentioned microRNA after bipolar radiofrequency ablation remained unclear, although bipolar radiofrequency ablation had high rate of sinus.

NCT ID: NCT04060498 Not yet recruiting - Psychosis Clinical Trials

Mindfulness Intervention and Relapse in Psychosis

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Practicing mindfulness is popular and well-accepted for its benefits in improving mental and physical health. In particular, its benefits in promoting resilience to stress and well-being have been shown in studies involving different psychiatric conditions, as well as preventing relapse in patients with depressive disorders. However, its role in relapse prevention among patients with psychosis has not been tested. The investigators therefore propose a multi-site, single-blind, 12-month randomized controlled trial in Hong Kong to examine the effectiveness of mindfulness intervention in prevention of relapse among 152 remitted psychosis patients.