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Prognostic Factors Affecting Recurrence and Disease-Free Survival After Surgical Resection for Cancer Rectum

Rectal Cancer Clinical Trial

Official title:
Predictors of Disease Free Survival After Curative Cancer Rectum Surgery

Clinical Trial Summary

Tumor recurrence after curative surgical resection for rectal cancer is a serious complication that greatly affects the overall morbidity and the outcome. This study aims to identify the different prognostic factors affecting recurrence and disease-free survival after surgery.

Clinical Trial Description

A retrospective analysis of patients operated for cancer rectum with curative intent from. Exclusion criteria will include patients with familial adenomatous polyposis, multiple synchronous or metachronous rectal cancers, and death within 3 months. Incomplete patients' files and patients that lost follow-up will be excluded. Demographic, histopathological, follow up and outcome data will be collected from completed patients' files. Demographics include age, gender, family history, and chief complaint at the presentation. Histopathological data include tumor grade, vascular-perineural invasion, the total number of lymph nodes removed, and positive lymph nodes. Lymph node ratio will be defined as the ratio of positive lymph nodes to the total number of retrieved lymph nodes in a histopathology specimen. Disease-free survival will be calculated for each patient based on the time of surgery to the time of recurrence detection. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06096493
Study type Observational
Source South Valley University
Contact Abdallah M Taha, MD
Phone +201011716497
Email abdallahsurgery@med.svu.edu.eg
Status Recruiting
Phase
Start date May 1, 2023
Completion date December 2023
View Details
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