Diazepam at the Active Phase of Labor

Pain Clinical Trial

Official title: Intravenous Injection of Diazepam at the Beginning of Active Phase of Labor

Status Not yet recruiting

Clinical Trial Summary

Prolonged labour can lead to increased maternal and neonatal mortality and morbidity due to increased risks of maternal exhaustion, postpartum haemorrhage and sepsis, fetal distress and asphyxia and requires early detection and appropriate clinical response. The risks for complications of prolonged labour are much greater in poor resource settings. Active management of labour versus physiological, expectant management, has shown to decrease the occurrence of prolonged labour. Administering sedatives during labour could also lead to faster and more effective dilatation of the cervix. Interventions to shorten labour, such as sedatives, can be used as a preventative or a treatment strategy in order to decrease the incidence of prolonged labour. As the evidence to support this is still largely anecdotal around the world. (Cochrane Database of Systematic Reviews 2013,CD009243.pub3.; Cochrane Database of Systematic Reviews 2012, CD009223.pub2.)

Hypothesis: Diazepam reduced the duration of labor and the severity of pain in labor.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Pain
• Prolonged Labour

• NCT number: NCT02232035
• Study type: Interventional
• Source: Navy General Hospital, Beijing
• Contact: Yunhai Chuai, Dr
• Phone: +86-18810892004
• Email: wangyh85@foxmail.com
• Status: Not yet recruiting
• Phase: Phase 2
• Start date: September 2014
• Completion date: September 2015