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Prolapse clinical trials

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NCT ID: NCT05072158 Terminated - Clinical trials for Urinary Incontinence

Pelvic Floor Disorders Among Sexual Minoritized Women

PRIDE
Start date: October 14, 2021
Phase:
Study type: Observational

The investigators aim to perform cognitive interviews to assess how pelvic floor disorders impact sexual functioning in women who have sex with women (WSW). As a secondary objective there will be cognitive interviews to assess perceptions of sexual function questionnaires such as Female Sexual Function Index (FSFI) and Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire-IUGA Revised (PISQ-IR) in WSW.

NCT ID: NCT05066737 Completed - Clinical trials for Pelvic Organ Prolapse

Evaluation of the Results of Lateral Suspension Surgeries Performed With the V-NOTES (Vaginal-Natural Orifice Transluminal Endoscopic Surgery) Technique

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

It was aimed to evaluate the quality of life and sexual function of patients by Pre- and postoperative POP-Q (Pelvic Organ Prolapse Quantification) staging and PISQ-12 (Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire) test of patients who underwent lateral suspension operation with V-NOTES (Vaginal-Natural Orifice Transluminal Endoscopic Surgery) Technique.

NCT ID: NCT05063331 Recruiting - Uterine Prolapse Clinical Trials

Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse

PREMIER
Start date: December 15, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term complications.

NCT ID: NCT05059249 Completed - Low Back Pain Clinical Trials

Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain

NCT ID: NCT05051033 Recruiting - Clinical trials for Mitral Valve Regurgitation

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

PRIMARY
Start date: February 21, 2022
Phase: N/A
Study type: Interventional

This is a prospective, multicenter, open-label, randomized trial comparing mitral valve (MV) transcatheter edge-to-edge repair (TEER) to surgical repair (1:1 ratio) in patients with primary, degenerative mitral regurgitation (MR). The trial will be conducted in the U.S., Canada, Germany and the United Kingdom, and is designed as a strategy trial. Thus, all devices legally marketed for TEER of primary degenerative MR in a particular country are eligible to be used in this trial.

NCT ID: NCT05042453 Recruiting - Clinical trials for Pelvic Organ Prolapse

Long-term Evaluation of the Efficacy and Safety of Splentis for the Treatment of Primary Apical Pelvic Organ Prolapse

SAXO
Start date: December 19, 2022
Phase:
Study type: Observational

This prospective, multi center cohort trial aims to evaluate the efficacy and safety of hysteropexy using Splentis via the vaginal route in primary uterine prolapse

NCT ID: NCT05012956 Completed - Clinical trials for Pelvic Organ Prolapse

Measuring Abdominal Wall Compliance During Gynecologic Laparoscopic Surgery

AbComp
Start date: October 12, 2022
Phase: N/A
Study type: Interventional

To measure abdominal wall compliance (AWC) during gynaecologic laparoscopy and assess its relation to the pelvic organ prolapse quantification (POP-Q) score of the same individual, and determine a relationship if present.

NCT ID: NCT05000957 Recruiting - Clinical trials for Pelvic Organ Prolapse

Pelvic Organs Prolapse Treatment Using Neodymium Laser

Start date: October 3, 2021
Phase: N/A
Study type: Interventional

The aim of this prospective study is investigation of efficiency and safety of medical device "Magic Max" for preoperative treatment of pelvic organs prolapse I-II degree of severity. To assess the condition of the vaginal walls and vulva before and after laser treatment, the following methods will be used: ultrasonography with Doppler ultrasonography, vaginal health index, histological examination, immunohistochemical examination, optical coherence tomography (OCT) (elastography). Pelvic Floor Distress Inventory Questionnaire (PFDI-20), The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12), International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF), Pelvic Floor Impact Questionnaire (PFIQ-7) will be used to collect feedback on changes in the participants life quality. Genetic testing of 12 gene variants will be carried out. Correlation of genes variants and treatment efficacy will be assessed. Total up to 135 participants with pelvic organs prolapse I-II degree of severity, or any other pathology of pelvic organs, which require surgical intervention will be involved in the study. Participants will be divided into three groups: group with anterior and/or posterior (A/P) colporrhaphy and laser preoperative treatment (laser treatment group), group with A/P colporrhaphy only (control group 1), and group with any other surgical intervention of pelvic area (control group 2), by 45 participants in each. The time intervals between tests will be the same for groups with A/P colporrhaphy, group with any other surgical intervention will be examined before and on the day of surgery without further observation. The main hypothesis of the study is improvement in condition of the vaginal walls after laser preoperative treatment compared with the control group 1.

NCT ID: NCT04996563 Completed - Clinical trials for Pelvic Organ Prolapse

Patient Educational Video for Pelvic Organ Prolapse

Start date: August 2, 2021
Phase: N/A
Study type: Interventional

This is a single-blinded, randomized controlled trial investigating if a patient educational video on pelvic organ prolapse improves patient understanding of this pelvic floor disorder and satisfaction in their healthcare decision making for its management.

NCT ID: NCT04980196 Completed - Urogenital Prolapse Clinical Trials

Is Preoperative Urodynamics Essential for Women With Pelvic Organ Prolapse

urodynaemics
Start date: September 20, 2020
Phase:
Study type: Observational

urodynamic investigation when added in the diagnostic work-up of women with lower urinary tract dysfunction with POP is debatable. This study was planned to determine the usefulness of preoperative urodynamic study in improving urological outcome following surgery in women with pelvic organ prolapse and urinary tract dysfunction.