Clinical Trials Logo

Clinical Trial Summary

There is a high incidence of women suffering from Primary Ovarian Insufficiency (POI). One of the most common treatments for POI is hormone replacement therapy (HRT), but HRT doesn't work well, and it has been shown to increase the risk of blood clots in the veins, ovarian cancer, and breast cancer. The ability of MSCs to differentiate into oocyte-like cells has been previously documented. Herein the purpose of this work is to evaluate the therapeutic potential of cell therapy in women suffering from POI.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03033277
Study type Interventional
Source Chinese Academy of Sciences
Contact Long Yan, Doctor
Phone +86-15650717331
Email yanlong@ioz.ac.cn
Status Recruiting
Phase Phase 1/Phase 2
Start date February 2016
Completion date July 2018

See also
  Status Clinical Trial Phase
Not yet recruiting NCT02871986 - Pubertal Induction in Individuals With Hypogonadism N/A
Recruiting NCT02322060 - In Vitro Activation of Dormant Follicles for Patients With Primary Ovarian Insufficiency
Recruiting NCT06167135 - Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
Active, not recruiting NCT04675970 - Long Term Follow up Patients With Premature Ovarian Failure ex Vivo Gene Therapy
Completed NCT04943354 - Associations of Combinations of Single-nucleotide Polymorphisms in Women With Premature Ovarian Failure N/A
Recruiting NCT03518918 - Establishing the Diagnosis Standard and Analysis the Risk Factors of POI in Chinese Women
Recruiting NCT05021094 - Clinical Observation on Kuntai Capsule in Treating Early-onset Ovarian Hypofunction Phase 4
Active, not recruiting NCT02795000 - Development a Predictive Nomogram for Primary Ovarian Insufficiency
Suspended NCT03021915 - Single Center, Prospective Controlled Pilot Study of the OvaPrime Procedure N/A
Completed NCT01436513 - A Study To Compare The Amount Of Premarin Components That Is Absorbed Into The Blood Of Japanese Healthy Postmenopausal Women Following Oral Administration Of Two Different Tablets Of Premarin Under Fast and Fed Conditions. Phase 1
Recruiting NCT06117982 - The Impact of Granulocyte Colony Stimulating Factor on Premature Ovarian Insufficiency Phase 2
Recruiting NCT02068976 - Observational Epidemiologic Study in Women With Premature Ovarian Failure (POF)
Completed NCT01973075 - Genetic Etiology in Premature Ovarian Insufficiency N/A
Completed NCT03568708 - Primary Ovarian Insufficiency: Phenotype and Optimal Treatment Phase 3
Not yet recruiting NCT02757469 - Oral Contraceptives as Infertility Treatments for Premature Ovarian Failure N/A
Completed NCT02091128 - Pregnancy Chances in Classic Galactosemia N/A
Terminated NCT00650754 - Study of Oral Dehydroepiandrosterone(DHEA) to Treat Previously Unexplained Infertility Phase 2/Phase 3
Recruiting NCT03496636 - Autologous Ovarian Tissue Transplantation N/A
Active, not recruiting NCT05737329 - Efficacy, Safety, and Tolerability of Higher Doses Estrogen Therapy in Women With Premature Ovarian Insufficiency Phase 1/Phase 2
Withdrawn NCT02922348 - Hormone Replacement for Premature Ovarian Insufficiency Phase 3