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Premenstrual Hormonal and Affective State Evaluation (PHASE) Project — PHASE Project  

Premenstrual Dysphoric Disorder Clinical Trial

Official title:
Premenstrual Hormonal and Affective State Evaluation (PHASE) Project

Clinical Trial Summary

PHASE is designed to evaluate neuroactive hormone trajectories across the menstrual cycle and endocrine, autonomic, and subjective responses to psychosocial stress in women suffering from severe PMS (i.e., premenstrual dysphoric disorder).

Clinical Trial Description

Female volunteers will be recruited from the community for participation in this 3-menstrual cycle study. In the first two menstrual cycles, study participants will chart their symptoms and and ovulation. Study participants will continue to perform ovulation testing during their third menstrual cycle in which they will attend one individualized task session and provide 8 serum samples at different timepoints across the menstrual cycle. Primary analyses will contrast neuroactive hormone trajectories across the menstrual cycle and stress reactivity according to study groups (PMDD vs healthy). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03862469
Study type Interventional
Source University of Illinois at Chicago
Contact
Status Completed
Phase N/A
Start date September 26, 2019
Completion date September 1, 2023
View Details
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