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Premature Birth clinical trials

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NCT ID: NCT04314440 Active, not recruiting - Clinical trials for Other Preterm Infants

Cognitive Processing in Preterm Infants and NICU Music Therapy

NICU-MT
Start date: January 2016
Phase: N/A
Study type: Interventional

Several positive physiological and behavioural outcomes have been observed in preterm infants exposed to music therapy during their stay at Neonatal Intensive Care Units (NICU). There is ample evidence in the literature showing that brief exposure to music can lead to superior performance on a host of cognitive tasks in laboratory settings in children, adolescent and adults. However, till date no study has examined the cognitive benefits of NICU music therapy in preterm infants. Further habituation tests have been employed to examine cognitive functioning in infants in laboratory setting but the same test have not been employed as a measure to examine early cognitive functioning in preterm infants. This project will be carried out to examine the benefits of NICU music therapy on the cognitive functioning of preterm infants born at 27- 33 weeks of gestational age. A randomized controlled research design will be employed to compare cognitive functioning between the treatment and control group at 18 - 24 months of corrected gestational age. The treatment group will be exposed to music therapy during their stay in NICU and the controlled group will be exposed to all standardized care available at our institution except music therapy. Habituation tests will be used to examine cognitive functioning of the preterm infants in groups at 18 - 24 months of gestational age.

NCT ID: NCT04313673 Active, not recruiting - Preterm Labor Clinical Trials

Transabdominal Cervical Length Predict Preterm Labor During Routine Antenatal Screening

Start date: March 10, 2020
Phase:
Study type: Observational

Sonographically, cervical length measurement is widely used in obstetrics. Studies have revealed that early detection of short cervix can be a predictor of predicting preterm labor. Transvaginal ultrasonography has been shown as a reference method for the recognition of the short cervix, as well as it may be useful in the transabdominal evaluation in the studies conducted. In addition to the advantages of transvaginal evaluation, it is time consuming and disadvantages of some women during anxiety and discomfort during this procedure. Transabdominal ultrasonography, which provides a non-invasive evaluation, is more preferred by some patients than transvaginal. The aim of this study is to investigate the value of the cervical length measured by transabdominal route, which is a more acceptable method for pregnant women, in predicting preterm birth.

NCT ID: NCT04304846 Recruiting - Preterm Birth Clinical Trials

AttachMent Preterm in the Loire Infant Follow-up Team

AMPLIFy
Start date: January 7, 2021
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to describe the attachment representations of children born prematurely at age 3 and 5 with regard to their neurocognitive and behavioral development.

NCT ID: NCT04304807 Completed - Clinical trials for Necrotizing Enterocolitis

Effect of Melatonin on Feeding Intolerance and Incidence of Necrotizing Enterocolitis in Preterm Infants

Start date: December 24, 2018
Phase: Phase 4
Study type: Interventional

Assesses the efficacy of melatonin in treatment of feeding intolerance in preterm infants, the time needed to reach full enteral intake, the incidence of necrotizing enterocolitis and measures the level of tumor necrosis factor-alpha as a marker of oxidative stress.

NCT ID: NCT04301518 Active, not recruiting - Preterm Birth Clinical Trials

Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcoMEs

PRIME
Start date: November 6, 2020
Phase: N/A
Study type: Interventional

This prospective, randomized, controlled study evaluates the safety and efficacy of a preterm birth (PTB) prevention strategy versus standard of care pregnancy management to reduce the incidence of adverse pregnancy outcomes.

NCT ID: NCT04301388 Withdrawn - Clinical trials for Preterm Delivery Within 7 Day After Admission

Management of Threatened Preterm Labor by Cervical Length-based Approach or Conventional Approach

Start date: January 22, 2020
Phase: N/A
Study type: Interventional

To compare the effectiveness of treatment of threatened preterm labor between transvaginal cervical length-based approach and conventional approach (Per vaginal examination)

NCT ID: NCT04300322 Recruiting - Preterm Birth Clinical Trials

Pessary Versus Progesterone in Singletons

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

This study compares the effectiveness of cervical pessary to vaginal progesterone for prevention of preterm birth in women with singleton pregnancies and a cervix ≤25 mm. Participants will be randomly assigned in a 1:1 ratio to receive cervical pessary or vaginal progesterone.

NCT ID: NCT04296591 Completed - Preterm Birth Clinical Trials

This Study Was to Investigate the Efficacy of Fetal Right Heart Doppler Findings in Determination of Pulmonary Maturity

Start date: January 1, 2017
Phase:
Study type: Observational [Patient Registry]

Objective: The aim of this study was to investigate the efficacy of fetal right heart doppler findings in determination of pulmonary maturity. Materials and Methods: Pregnant women refered to the Department of Obstetrics and Gynecology at Karadeniz Technical University were included in the study. Pregnant women with pregestational or gestational diabetes mellitus, morbid obesity, thyroid dysfunction and fetal abnormality aneuploidy were not included in the study. The study was planned on women with late preterm and term pregnancy. Late preterm cases between 34-37 weeks were included in study group and term cases over 37 weeks were in control group. The doppler findings of main pulmonary artery and right pulmonary artery, mitral valve e/a wave ratio and lamellar body count were determined as the main outcomes. During caesarean section, 5cc amniotic fluid was taken to measure lamellar bodies count. Perinatal results of patients were recorded. p<0.05 was considered as statistical significance.

NCT ID: NCT04295564 Active, not recruiting - Premature Birth Clinical Trials

Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function

Start date: January 10, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

This is a study to see if an extra 2 weeks of continuous positive airway pressure (CPAP) in stable preterm infants in the neonatal intensive care unit (NICU) can cause increased lung growth and lung function in the infants as measured at 6 months of age by pulmonary function testing.

NCT ID: NCT04295187 Completed - Preterm Birth Clinical Trials

Health of Pessary Versus Progesterone Supplement for Preventing Preterm Birth Children

Start date: March 6, 2020
Phase:
Study type: Observational

To give strong recommendations on the efficacy and safety of vaginal progesterone versus cervical cerclage, we conduct this study to investigate the physical and mental development of children from vaginal progesterone versus cervical cerclage. Based on our research (Dang et al., 2019), the twin pregnancies with cervical lengths less than 38mm were randomly assigned to receive vaginal progesterone or cervical cerclage, which leads to the similarity in characteristics of these two groups. Hence, the result of analyzing these offsprings would be preciously valuable.