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Pregnancy clinical trials

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NCT ID: NCT03783663 Completed - Pregnancy Clinical Trials

Sleep Self-management in Pregnancy Using a Personalized Health Monitoring Device

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Pregnancy-associated sleep disorders are a common acute experience in pregnancy experienced by up to 82% of women. Sleep disorders are associated with increased risk for pre-eclampsia, gestational diabetes, longer labor, cesarean birth, and postpartum depression, and are higher among pregnant women of lower socioeconomic status. Traditional clinical management of sleep disorders in pregnancy includes education and counseling on sleep hygiene and sleep positioning, dietary modifications, relaxation, iron supplementation, weight management, and physical activity, yet education-based behavioral interventions show minimal effectiveness for improving sleep among pregnant women. These methods typically do not incorporate objective self-monitoring, which is an important behavior change technique. In pregnancy, objective self-monitoring on a day-to-day basis is particularly important as sleep disorders may worsen as pregnancy progresses. Computer-based personalized health monitoring (PHM) devices may serve as an effective tool with which pregnant women can self-manage sleep through incorporation of regular feedback. This strategy may be beneficial not only for women with pregnancy-associated sleep disorders but also for pregnant women with less severe sleep disruptions that experience daytime sleepiness, fatigue, and decreased quality of life. PHM devices have been used to promote weight loss, diet, and physical activity changes but no studies have specifically targeted sleep among pregnant women. The purpose of this pilot study is to establish the feasibility and acceptability of conducting a 12-week intervention for sleep self-management with pregnant women using a PHM device, in order to refine the intervention for a larger, randomized trial.

NCT ID: NCT03763071 Completed - Pregnancy Clinical Trials

Sleep Disturbances in the 2nd and 3rd Trimester

Start date: December 7, 2018
Phase:
Study type: Observational

Sleep disorders and disturbances are mostly underestimated in clinical practice. Moreover, this problem is generally neglected by the pregnant themselves. Today, it is important to underline any problem that may have an affect to improve the quality of life during pregnancy. This study assesses the sleep quality, insomnia patterns and obstructive sleep apnea in the second and third trimesters of pregnancy.

NCT ID: NCT03744364 Completed - Pregnancy Clinical Trials

Low-dose Vaginal Misoprostol Versus Vaginal Dinoprostone Insert for Induction of Labor

MADUTER
Start date: June 1, 2014
Phase: Phase 4
Study type: Interventional

Purpose: To compare the efficacy and safety of low-dose protocol of vaginal misoprostol and vaginal dinoprostone insert for induction of labor in women with post-term pregnancies. Methods: The investigators designed a prospective, randomized, open-labeled, blinded for the end-point evaluators trial including women of at least 41 weeks of gestational age with uncomplicated singleton pregnancies and Bishop score lower than 6. Participants were randomized into dinoprostone or misoprostol groups in a 1:1 ratio. Baseline maternal data and perinatal outcomes were recorded for statistical analysis. Successful vaginal delivery within 24 hours was the primary outcome variable.

NCT ID: NCT03735043 Completed - Pregnancy Clinical Trials

Cardiac Output Monitoring by ccNexfin© in Pregnant Women

CoNex
Start date: July 2, 2019
Phase: N/A
Study type: Interventional

Variations of cardiac output are frequent in pregnant women during obstetrical procedures, and may participate to poor foetal outcomes through decrease of uteroplacental bloodflow. Thus, monitoring maternal cardiac output appears of major interest, as it would open the way to early initiation of hemodynamic supportive management. The ccNexfin© is a non-invasive hemodynamic monitoring device, whose relevance for continuous monitoring of cardiac output has been reported in a non-pregnant population. The hypothesis is that ccNexfin© gives acceptable measurement of maternal cardiac output in pregnant women.

NCT ID: NCT03729076 Completed - Pregnancy Clinical Trials

Crystalloid Versus Colloid Rapid Co-load for Cesarean Delivery Under Spinal Anesthesia

Start date: November 16, 2018
Phase: N/A
Study type: Interventional

The study aims to compare crystalloid co-loading and colloid co-loading in parturients receiving prophylactic phenylephrine infusion during cesarean delivery in terms of the incidence of hypotension.

NCT ID: NCT03719846 Completed - Pregnancy Clinical Trials

Continuous Sample Collection Study

CSC
Start date: November 5, 2018
Phase:
Study type: Observational

This study will provide urine cycles from both pregnant and not pregnant volunteers to maintain the SPD sample bank. Study volunteers, seeking to conceive will be provided with Clearblue Ovulation product to help them pinpoint their most fertile time and aid conception. All volunteers will provide daily early morning urine samples throughout the study period and keep a study diary of menses and pregnancy test results for 1 menstrual cycle. Urine samples will be received in the clinical laboratory and aliquoted into 2.25ml amounts at stored at -80˚C until required. The study will also gather optional information from volunteers regarding a woman's general health and stress levels when trying to conceive. This will be used to study the relationship between general health, stress and conception.

NCT ID: NCT03690271 Completed - Pregnancy Clinical Trials

Study PIEB vs PIEB: the Dose is it Variable According to the Patients

DOPABIEB
Start date: December 1, 2017
Phase:
Study type: Observational

the main objective of this study is to compare the effectiveness of three groups of epidurals with three different programmed intermittent epidural bolus (PIEB)settings.

NCT ID: NCT03670537 Completed - Pregnancy Clinical Trials

Iron Parameters in Non-anemic First Trimester Gravidas

Start date: February 7, 2018
Phase:
Study type: Observational

The purpose of the study is to see the percentage of non-anemic, first trimester gravidas presenting to their obstetricians, who are iron deficient.

NCT ID: NCT03668184 Completed - Pregnancy Clinical Trials

What Are the Predictive Factors for Preeclampsia in Oocyte Recipients? - PREROVE

PREROVE
Start date: January 2, 2018
Phase:
Study type: Observational

The main goal is to determine which risk factors develop preeclampsia in this specific group of oocyte recipients.

NCT ID: NCT03665012 Completed - Clinical trials for Pregnancy, Puerperium and Perinatal Conditions

The Pediatric Development Clinic Study

PDC
Start date: April 1, 2017
Phase:
Study type: Observational [Patient Registry]

Many preterm, low birth weight and other high-risk infants are surviving the early neonatal period. However, upon discharge from the neonatal units, this at-risk population has little support for their health, nutrition and development in the community. To address this emerging need, Partners In Health in collaboration with the Ministry of Health and UNICEF, has created a pediatric developmental clinic (PDC) to follow the high-risk infants after discharge from hospitals and health centers.