Left Ventricular and Endothelial Function in Preeclampsia

Preeclampsia Clinical Trial

Official title:

Left Ventricular and Endothelial Function in Preeclampsia, a Case Control Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00201500
• Other study ID #: PEETLV
• Status: Completed
• Phase: Phase 1/Phase 2
• First received: September 16, 2005
• Last updated: August 3, 2016
• Start date: October 2004
• Est. completion date: March 2006

Study information

• Verified date: August 2016
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway: Norwegian Social Science Data Services
• Study type: Observational

Clinical Trial Summary

The purpose of this study is (1) to examine whether the left ventricular function is impaired in women with preeclampsia relative to healthy pregnant controls, (2) to examine whether the endothelial function is impaired in women with preeclampsia relative to healthy pregnant controls, and (3) to examine whether there is a post partum impairment in left ventricular and endothelial function.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 39
• Est. completion date: March 2006
• Est. primary completion date: December 2005
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• >18 years of age

• Case: Clinical diagnosis of preeclampsia,

• Control: Systolic BP <140 mmHg and diastolic BP <90 mmHg

Exclusion Criteria:

• Known hypertension or other cardiovascular disease

• Diabetes/gestational diabetes

• Multiple gestation

Study Design

Observational Model: Case Control

Related Conditions & MeSH terms

• Pre-Eclampsia
• Preeclampsia

Locations

Country	Name	City	State
Norway	NTNU	Trondheim

Sponsors (2)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology	Central Norway Regional Health Authority

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Tyldum EV, Backe B, Støylen A, Slørdahl SA. Maternal left ventricular and endothelial functions in preeclampsia. Acta Obstet Gynecol Scand. 2012 May;91(5):566-73. doi: 10.1111/j.1600-0412.2011.01282.x. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Left Ventricular Function		3 months	No
Primary	Endothelial Function		3 months	No