Clinical Trials Logo

Clinical Trial Summary

Cerebral palsy (CP) concerns 2 children out of 1000 in the general population (SCPE 2002). It is the main cause of postural and motor deficits in children.

During the past 20 years, the postural deficits exhibited by these children have been attributed to various factors :

1. neuromuscular functions

2. sensory integration

3. muscular-squeletic functions.

The common point of all these studies is the existence of immature motor patterns, probably related to an inability to implement more elaborated and adapted motor patterns with respect the task to perform.

CP children do not develop the characteristics of the plant grad locomotion. They exhibit a uniform muscular activation with a high level of co-activation. Locomotion is generally characterized by an increase of stretching reflexes at short latencies and by a low level of activation associated to a low modulation of gastrocnemius muscles..

These data also suggest that it is the control of the temporal rather than the spatial parameters of the head which are mainly altered in CP children.

Even though static postural control and locomotion are considered as automatic processes, this control requires, however, a significant amount of attentional resources.

Within this context, the amount of attentional resources which need to be solicited can provide information on two complementary dimensions. On one hand, on the level of automaticity of postural control and/or locomotion when subjects' attention is oriented toward another task. On the other hand, on the cognitive cost of postural control and/or locomotion, depending on children age, that is, as a function of their level of maturation and of the nature and importance of their sensory-motor deficits. When the amount of required attentional resources is reduced, postural control and/or locomotion is considered as automatic processes with a low cognitive cost.

The dual task paradigm in which subjects have to simultaneously process a cognitive (e.g. Stroop task) and a postural or motor task (e.g., standing upright on a force platform) is generally used to investigate these questions.

How an appropriate allocation of attention is performed as a function of the cognitive and postural/motor tasks is important in the developmental process of posture and locomotion. It seems to be even more crucial in CP children and more generally in pathology.

The main goal of the present project is to investigate the contribution of attentional processes in postural control and locomotion of CP children as compared to control healthy children.


Clinical Trial Description

Within this scientific and clinical context, we hypothesize:

- That CP children will be less stable than healthy children (in control situation) and that the attentional cost for controlling static posture will be higher.

- On the basis of Olivier et al.'s work (2008) showing in adults and children aged 4 to 11 that postural control is better when attention is oriented toward a video film (i.e., decrease of the attentional demand allocated to the control of static posture), we predict that CP children will be more stable in dual task situation with visual or sound distractors than when focusing attention on postural control alone.

- We also predict that an additional cognitive task (adapted Stroop task), by increasing the attentional demand, will induce a deficit of postural control confirming Reilly et al.'s results (2008b).

On the same basis, we will also investigate the attentional cost of locomotion.

Exploratory study of dynamic equilibrium during locomotion in the same conditions.

Investigation of posture in the following conditions:

1. without attentional distractors and without additional cognitive task (control condition)

2. with attentional visual and sound distractors (video film)

3. with sound attentional distractor alone (sound track of the video film)

4. with an additional cognitive task (Stroop task adapted for children).

Considering the goals of this research project, no serious undesirable event is expected to occur. However, falls may occur accidentally while rising or descending from the force platform, during static posture, or during locomotion. Consequently, in addition to the experimenter, a physiotherapist or someone of the medical staff will be present during all experimental recordings.

The environment will be also organized to the secure the experimental room by excluding all potentials dangerous or non necessary objects. Whenever necessary, the potentials falls will be reported and declared to the health authorities. ;


Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care


Related Conditions & MeSH terms


NCT number NCT01799304
Study type Interventional
Source University Hospital, Grenoble
Contact
Status Completed
Phase Phase 3
Start date February 2013
Completion date December 2015

See also
  Status Clinical Trial Phase
Completed NCT03780296 - Implementing Technology Enhanced Real Time Action Observation Therapy in Persons With Chronic Stroke N/A
Not yet recruiting NCT05535504 - The Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation for Upper-limb Motor Function Recovery in Subcortical and Brainstem Stroke N/A
Recruiting NCT03605381 - MORbidity PRevalence Estimate In StrokE
Recruiting NCT05163210 - Effectiveness of AOT Based on Virtual Reality in Stroke Rehabilitation. N/A
Completed NCT04658745 - Effects of Theta Burst Stimulation on Modulation of Mirror Illusion-induced Rhythm Suppression in Stroke N/A
Not yet recruiting NCT04105322 - Effects of Kinesio Taping on Balance and Functional Performance in Stroke Patients N/A
Completed NCT02918890 - Intensive Unimanual (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegia N/A
Completed NCT02254876 - Effectiveness of NeuroMuscular Taping on Painful Hemiplegic Shoulder N/A
Completed NCT01864811 - Effect of Baby-CIMT in Infants Younger Than 12 Months N/A
Terminated NCT01567332 - Evaluation of Walking After Repetitive Transcranial Magnetic Stimulation (rTMS) Inhibitory 1Hz in Vascular Hemiplegia N/A
Completed NCT01016496 - New Perspectives in the Rehabilitation of Children With Motor Disorders : the Role of the Mirror Neuron System N/A
Recruiting NCT05564182 - High Intensity Laser Therapy in the Treatment of Hemiplegic Shoulder Pain N/A
Recruiting NCT06059781 - Effects of Auditory and Visual Cueing on Sensorimotor Recovery and Gait in Hemiplegia N/A
Terminated NCT03284606 - Effect of Taping in the Hemiplegic Patient With a Deficit of the Footbrowers N/A
Terminated NCT04613648 - Ultrasonographic Assessment of Painful and Stiff Hemiplegic Shoulder in Terms of Adhesive Capsulitis
Completed NCT05596513 - Motor Learning Approaches From Working on a Vertical Surface in Hemiplegic Children's Upper Limb Motor Skills N/A
Terminated NCT02592759 - Effects of Upper Extremity Rehabilitation Using Smart Glove in Stroke Patients N/A
Completed NCT01447810 - Constraint-Induced Movement Therapy in a Pediatric Oncology Population N/A
Completed NCT01232218 - Treatment Protocol for Hemiplegic Shoulder Pain N/A
Completed NCT05667025 - Comparison of the Effects of Cycling FES and Conservative Rehabilitation Therapy on Stroke Patients N/A