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Postoperative Pain clinical trials

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NCT ID: NCT06015165 Not yet recruiting - Postoperative Pain Clinical Trials

Outcomes for Anesthesiologist-Led Care of Analgesic Protocol in Anorectal Surgery

Start date: May 10, 2024
Phase: N/A
Study type: Interventional

This will be an open, prospective, parallel-group, randomized controlled trial. Patients scheduled for complex anorectal surgery under general anesthesia will be enrolled, and the perioperative analgesia mode led by anesthesiologists will be established. Compared with the perioperative analgesia mode led by surgeons, the efficacy and safety of analgesia, quality of life and satisfaction of patients will be evaluated. This study is aimed at the feasibility and efficiacy of anesthesiologist-led treatment mode in the management of moderate and severe pain in patients after complex anorectal surgery.

NCT ID: NCT06008002 Not yet recruiting - Postoperative Pain Clinical Trials

Evaluation of the Efficacy of Regional Anaesthesia for Analgesia After Laparoscopic Cholecystectomy

Start date: August 25, 2023
Phase: N/A
Study type: Interventional

Postoperative pain is important for patient comfort, wound healing and earlier mobilisation. Different procedures are used by clinicians for this purpose. Intravenous and regional anaesthesia techniques can be used for this purpose in patients undergoing laparoscopic cholecystectomy.

NCT ID: NCT05999721 Not yet recruiting - Postoperative Pain Clinical Trials

The Effect of Superficial Parasternal Intercostal Plane Block on Pulmonary Function Tests After Cardiac Surgery

PIPACS
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

In adult patients undergoing cardiac surgery, does adding an sPIP block to standard care compared to standard care alone result in a smaller decrease in PFTs?

NCT ID: NCT05997355 Not yet recruiting - Postoperative Pain Clinical Trials

Preoperative Gabapentin for Cosmetic Breast Surgery

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare postoperative pain and opioid consumption in patients who undergo cosmetic breast surgery and are treated preoperatively with gabapentin. The main questions to answer are the amount of postoperative pain on a scale of 0-10 and amount of opioids consumed postoperatively. Participants will be randomized into two groups: treatment vs no treatment. Treatment group will receive 600mg of gabapentin preopreatively. Researchers will compare treatment vs no treatment group to determine the effects of preoperative gabapentin on postoperative pain management and opioid consumption.

NCT ID: NCT05979493 Not yet recruiting - Postoperative Pain Clinical Trials

QL Block in Laparoscopic Myomectomy

Start date: August 1, 2024
Phase: Phase 4
Study type: Interventional

This study aims to determine the efficacy of a quadratus lumborum (QL) block in decreasing postoperative pain in patients undergoing myomectomy for uterine fibroids. A QL block is a temporary anesthetic injection in the quadratus lumborum muscle, a muscle in the lower back, that has been previously shown to significantly reduce postoperative pain levels in patients undergoing abdominal and pelvic surgery. Because of its demonstrated effects, the QL block is becoming a standard of anesthesia and surgical care. Since participants will be undergoing a myomectomy procedure, the investigators believe that participants may qualify to participate in this study. The investigators will be comparing patients who receive the QL block (in addition to standard anesthesia and postoperative pain care) with patients who do not receive the QL block (in addition to standard care). The participants will be randomly assigned to one of the two groups and may or may not actually receive the block.

NCT ID: NCT05964985 Not yet recruiting - Postoperative Pain Clinical Trials

Effect of Quadratus Lumborum Block With Compound Lidocaine and Esketamine on Pain After Colorectal Surgery

Start date: August 6, 2023
Phase: N/A
Study type: Interventional

Purpose: To explore effects of ultrasound-guided quadratus lumborum block with compound lidocaine and esketamine on postoperative pain after colorectal surgery.

NCT ID: NCT05943613 Not yet recruiting - Postoperative Pain Clinical Trials

Efficacy of Intrathecal Clonidine Versus Neostigmine as Adjuvants to Bupivacaine on Postoperative Maternal and Fetal Outcomes After Elective Cesarean Section

Start date: December 1, 2023
Phase: Phase 1
Study type: Interventional

The delivery of the infant into the arms of a conscious and pain free mother is one of the most exciting and rewarding moments in medicine. Neuraxial anesthesia is now the preferred technique for lower segment cesarean sections (LSCS). Although epidural, spinal, continuous spinal, and combined spinal-epidural techniques have all been advocated, most cesarean sections are performed under single-shot spinal anesthesia. Even when a long acting local anesthetic like bupivacaine is used, the duration of spinal anesthesia (SA) is short and higher doses of analgesics are required in the postoperative period. Therefore, achieving a subarachnoid block that provides high quality postoperative analgesia of consistently prolonged duration is an attractive goal.

NCT ID: NCT05940454 Not yet recruiting - Postoperative Pain Clinical Trials

Pericapsular Nerve Group Block in Shoulder Surgery

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Dear Patient, You have been scheduled for shoulder surgery by your surgeon. This surgery is performed under general anesthesia, that is, by putting the patient to sleep, and then moderate or severe pain is experienced. In order to prevent this post-operative pain, painkillers are given through the vascular access or the operated area, namely the shoulder, is locally anesthetized. Many techniques are used to numb the shoulder locally. One of these techniques is the pericapsular nerve group block and it is a newly defined technique. In this block, some of the nerves that carry the pain sensation of the shoulder are temporarily anesthetized with local anesthetics. This study will investigate how effective this block is in reducing pain associated with shoulder surgery.

NCT ID: NCT05905861 Not yet recruiting - Postoperative Pain Clinical Trials

Scalpel Versus Diathermy for Transverse Abdominal Incision in First Elective Caesarean Section

Start date: July 2023
Phase: N/A
Study type: Interventional

The objective of this study will be to compare two methods of skin incisions during the first caesarean section (CS), that is scalpel and diathermy, assessing differences in blood loss during incision, incisional time, total surgery time, post-operative pain, wound healing, complications, and cosmetic outcomes.

NCT ID: NCT05840406 Not yet recruiting - Postoperative Pain Clinical Trials

Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The primary purpose of this study is to determine whether the addition of a TAP block to standard analgesia after the cesarean delivery will impact postoperative wound healing and attenuate postoperative stress and immune response. Random allocation of participants in 3 groups: group SA (standard analgesia), group L (TAP block with levobupivacaine), and group D (TAP block with levobupivacaine + dexmedetomidine). All participants will undergo elective cesarean section through Pfannestiel incision under spinal anesthesia. They will receive standard postoperative pain management with acetaminophen, nonsteroidal anti-inflammatory drugs, and tramadol. Groups L and D will additionally receive bilateral ultrasound-guided TAP block with 20 ml 0,25% levobupivacaine or with 20 ml 0,25% levobupivacaine with the addition of 0,5 μg/kg dexmedetomidine. TAP block will be performed in the theatre immediately after the cesarean delivery. Venous blood samples will be collected before the surgery and on the third postoperative day. Complete blood count and serum cortisol levels will be measured. REEDA scale will be used for assessing wound healing.