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Postoperative Pain clinical trials

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NCT ID: NCT05344677 Completed - Postoperative Pain Clinical Trials

Shoulder Pain and Post Gynecologic Laparoscopic Recovery

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

The present study aims to investigate the effect of postoperative trendelenburg position versus warm pad application and deep breathing technique on shoulder pain intensity and post gynaecologic laparoscopic recovery

NCT ID: NCT05340725 Recruiting - Postoperative Pain Clinical Trials

Rectal Dexmedetomidine Niosomes for Postoperative Analgesia in Pediatric Cancer Patients.

DEX-NANO
Start date: May 1, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Applying nanotechnology in drug delivery systems improved the bioavailability and kinetic profile of drugs in biological systems

NCT ID: NCT05324995 Completed - Postoperative Pain Clinical Trials

Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee Arthroplasty

Start date: January 1, 2021
Phase: Phase 2
Study type: Interventional

This study is a randomized-clinical-trial on 146 patients candidate for total knee arthroplasty (TKA) who were randomly allocated to three treatment groups, including 1) a cocktail consisting of bupivacaine, morphine, epinephrine, and ketorolac (n=48), 2) only epinephrine (placebo group) (n=49), and 3) 400mg celecoxib orally (control group) (n=49) using Random Allocation software. The injections and oral therapy were performed within 15 minutes before the surgical procedure. The study's primary outcome was the Knee Society Score (KSS) calculated at baseline, within six weeks and six months postoperatively. Range of motion (ROM) and Visual Analogue Scale (VAS) to assess pain intensity as the other primary outcomes were evaluated before the procedure, within 24 hours, 48 hours, and six weeks postoperatively.

NCT ID: NCT05324891 Completed - Postoperative Pain Clinical Trials

Dexmedetomidine Versus Fentanyl for Sedation of Postoperative Mechanically Ventilated Neonates

Start date: January 2016
Phase: Phase 2
Study type: Interventional

Newborn infants experience pain after surgical procedures,prevention and management of pain in neonates is important due to its deleterious consequences. Fentanyl is a widely used analgesic which promotes rapid analgesia,however, is not free of adverse effects including chest wall rigidity, hypothermia, hypotension, respiratory depression and tolerance.Dexmedetomidine is a selective α 2-adrenergic agonist can cause sedation, anxiolysis, analgesia and minimal respiratory depression.Therefore, the objective of the study is to evaluate the safety and efficacy of dexmedetomidine compared to fentanyl in postoperative mechanically ventilated neonates.

NCT ID: NCT05324215 Recruiting - Postoperative Pain Clinical Trials

Transversalis Fascia Plane Block and Rectus Sheath Block in Renal Transplantation Donors

Start date: February 17, 2022
Phase: N/A
Study type: Interventional

Transversalis fascia plane block (TFPB) is a relatively new, easy-to-apply and safe regional anesthesia technique used to provide postoperative analgesia in various surgeries. It has been shown that TFPB and rectus sheath block (RSB) administration reduces opioid consumption and related side effects in patients undergoing surgery with general anesthesia. To our knowledge, there is no study examining TFPB in donor nephrectomy. The investigators aimed to prospectively examine the effect of TFPB and RSB on opioid consumption in postoperative period on donors who will undergo laparoscopic nephrectomy in renal transplantation surgery.

NCT ID: NCT05318729 Not yet recruiting - Postoperative Pain Clinical Trials

Use of a Vibration Tool for Postoperative Pain Control in Distal Radius Fractures

Start date: March 2025
Phase: N/A
Study type: Interventional

The purpose of this research study is to determine if using a vibration tool improves pain control after surgical treatment of distal radius fracture. Additionally, the investigators would like to determine if this tool has any impact on consumption of pain medications postoperatively.

NCT ID: NCT05312957 Completed - Postoperative Pain Clinical Trials

Efficacy of Erector Spinae Plane Block in Caridac Surgery

Start date: October 14, 2020
Phase: N/A
Study type: Interventional

Introduction: Opioid-based pharmacological treatment is frequently used in the treatment of pain after coronary artery bypass graft (CABG) surgery. If adequate postoperative analgesia is not provided in such surgeries, pulmonary and cardiovascular complications may develop. This study aimed to provide effective analgesia and reduce postoperative opioid consumption by applying preemptive erector spinae plane (ESP) block. Methods: A total of 50 patients who underwent CABG surgery were included in this prospective randomized controlled study. Patients were randomly divided into two groups: the ESP group and the control group. The intervention to the ESP group was applied bilaterally at the T5 level before the surgery. The primary outcome was postoperative opioid consumption; the other outcomes included visual analog scale scores, intraoperative opioid consumption, and duration of hospital stay.

NCT ID: NCT05308797 Completed - Postoperative Pain Clinical Trials

Combine Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Coronary Bypass Surgery

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Even though Erector Spinae Plane (ESP) Block is shown to be efficient in cardiac surgery, the Combine Serratus Anterior Plane (CSAP) Block is still controversial if it has an efficient analgesic effect for sternotomy and drain tube pain relief. This study aims to compare ESP block and CSAP block for postoperative analgesia in coronary bypass surgery patients.

NCT ID: NCT05308420 Completed - Postoperative Pain Clinical Trials

PENG Block vs Intrathecal Morphine in Total Hip Arthroplasty

Start date: April 3, 2022
Phase: Phase 4
Study type: Interventional

To compare the impact of pericapsular nerve group (PENG) block to intrathecal morphine on postoperative analgesia, motor function and side effects in patients undergoing primary total hip arthroplasty under spinal anesthesia.

NCT ID: NCT05308251 Completed - Postoperative Pain Clinical Trials

Comparison of Hernia Sac Ligation Versus Invagination

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Management of indirect hernial sac in inguinal hernia repairs has long been a subject of debate among general surgeons. Although hernial sac high ligation (HL) is a time-honored concept in groin hernia surgery, non-ligation/invagination is gaining more popularity. The aim of this study is to compare the effects of hernia sac ligation and invagination in patients with Lichtenstein mesh hernioplasty (LMH). Also, investigators aimed to investigate the possible association between the hernial defect size and postoperative early pain in both groups.