Postoperative Complications Clinical Trial
Official title:
The Effect of Gabapentin on Postoperataive Pain ,Morphine Sparing Effect and Preoperative Anxiety in Bariatric Surgical Patients
The evidence regarding effects of pain modulator like gabapentin on postoperative pain after sleeve gastrctomy is sparse. Gabapentin has anti-hyperalgesic and postoperative opioid-sparing properties.This study will highlight the effectiveness of preoperative use of gabapentin for postoperative pain management in morbidly obese patients.
Research Problem: Laprocopic sleeve gastrectomy is the most common surgical procedure
performed for reducing weight in morbidly obese patients. Laparoscopic surgery is considered
to be less invasive than open surgery. The treatment of pain in obese patients is a
challenge. Administering opioids, can have an increasing effect of respiratory depression in
patients already at risk of sleep apnea. The evidence regarding effects of pain modulator
like gabapentin on postoperative pain after sleeve gastrctomy is sparse. Gabapentin has
anti-hyperalgesic and postoperative opioid-sparing properties. The analgesic effect of
gabapentin appears to be related to the surgical procedure undertaken, a more
procedure-specific evaluation is needed for different types of surgeries..
Research Significance: This study will highlight the effectiveness of preoperative use of
gabapentin for postoperative pain management in morbidly obese patients.
Research Objectives: To evaluate the effect of preoperative administration of gabapentin on
postoperative pain, postoperative morphine consumption and preoperative anxiety in patients
coming for laparoscopic sleeve gastrectomy.
Research Methodology:
Inclusion criteria: ASA I and II, Age 18-50 years, either sex, Planned Surgical procedure
laparoscopic sleeve garstectomy, BMI 30-45 . Exclusion criteria: Patients taking any
sedative, tranquillizers , history of sleep apnoea ,contraindications to gabapentin, Methods
Patients will be randomly assigned into two groups, Group-Control and , Group- Gabapentin of
25 each. Anesthesia and postoperative course will be standardized. VAS scale will be used
for assessment of preoperative anxiety and postoperative pain. Post operatively pain
assessment and morphine consumption will be performed for 24 hours in PACU and ward
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03181620 -
Sedation Administration Timing: Intermittent Dosing Reduces Time to Extubation
|
N/A | |
| Recruiting |
NCT04205058 -
Coffee After Pancreatic Surgery
|
N/A | |
| Completed |
NCT06425601 -
A Comparison of Silicone Versus Polyvinylchloride (PVC) Drains Following VATS Lobectomy
|
N/A | |
| Completed |
NCT02565420 -
Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial
|
N/A | |
| Recruiting |
NCT04519593 -
ABSOLUTELY: A Temporary Uterine Blood Supply Occlusion for Laparoscopic Myomectomy in Patients With UTErine LeiomYoma
|
N/A | |
| Completed |
NCT03662672 -
Rib Raising for Post-operative Ileus
|
N/A | |
| Completed |
NCT03787849 -
Epigenetics in PostOperative Pediatric Emergence Delirium
|
N/A | |
| Active, not recruiting |
NCT05886387 -
a Bayesian Analysis of Three Randomised Clinical Trials of Intraoperative Ventilation
|
||
| Not yet recruiting |
NCT06351475 -
Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy
|
N/A | |
| Not yet recruiting |
NCT05052021 -
The South African Coronavirus Disease of 2019 (COVID-19) Surgical Outcomes Study
|
||
| Not yet recruiting |
NCT03639012 -
Outcomes of Carbohydrate Loading Paediatric Patients Preoperatively for Tonsillectomy and Adenoidectomy
|
N/A | |
| Not yet recruiting |
NCT03591432 -
A Trial Comparing Transnasal humidified Rapid insufflation Ventilatory Exchange (THRIVE) and Apneic Oxygenation With Facemask Ventilation in Elderly Patients Undergoing Induction of Anaesthesia.
|
N/A | |
| Not yet recruiting |
NCT03275324 -
Use of Integrated Pulmonary Index to Predict Post-Operative Respiratory Adverse Events in High Risk Patients
|
N/A | |
| Recruiting |
NCT02763878 -
Uncut Roux-en-y Anastomosis Reduce Postoperative Complication and Improve Nutritional Status After Distal Gastrectomy
|
Phase 3 | |
| Completed |
NCT02947789 -
Predictive Model for Postoperative Mortality
|
N/A | |
| Completed |
NCT02891187 -
Visits Versus Telephone Calls for Postoperative Care
|
N/A | |
| Completed |
NCT02766062 -
Effects of Propofol and Sevoflurane on Early POCD in Elderly Patients With Metabolic Syndrome
|
N/A | |
| Not yet recruiting |
NCT02542423 -
Endocan Predictive Value in Postcardiac Surgery Acute Respiratory Failure.
|
N/A | |
| Recruiting |
NCT01934049 -
Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
|
Phase 4 | |
| Enrolling by invitation |
NCT01744938 -
Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice
|
Phase 3 |