Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study

Postoperative Complications Clinical Trial

Official title:

Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02961075
• Other study ID #: post2016taper
• Status: Completed
• Phase: N/A
• First received: November 9, 2016
• Last updated: January 23, 2017
• Start date: May 2016
• Est. completion date: November 2016

Study information

• Verified date: November 2016
• Source: The Second Affiliated Hospital of Dalian Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study

Description:

Fiberoptic bronchoscopy (FOB) is the essential procedures for diagnosis and treatment of respiratory diseases。 Fever following FOB has been frequently reported. Fever is usually caused by patient discomfort and delay recovery from illness, or even worse. The reported frequency of this complication ranges from 1 to 20%. According to previous reports, postbronchoscopy fever is associated with advanced age, the presence of abnormal bronchoscopic findings,documented endobronchial obstruction, bronchoscopic intervention for malignancy, BAL, bronchial brushing, endotoxin contamination during bronchoscopy, instillation of topical anesthetic through the bronchoscope, abnormal differential cell counts in the BAL fluid (BALF), bacterial growth in the BALF culture,and the severity of bleeding. At present, guidelines recommend sedation and analgesia combined with airway surface anesthesia for Fiberoptic bronchoscopy. laryngeal spray and cricothyroid anesthesia often used in clinical.Cricothyroid local anesthesia has a good effect, but it is an invasive operation, this is risk factors for fever after bronchoscopy.Therefore, to compare fever in the two kinds of airway anesthesia on Bronchoscopy . So as to provide the local anesthesia method with little influence on the patient.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 160
• Est. completion date: November 2016
• Est. primary completion date: November 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 75 Years

Eligibility

Inclusion Criteria:

• ASA I-III

Exclusion Criteria:

• use of immunosuppressive agents or corticosteroids

• body temperature 37.3°C during the 24 h prior to FOB,intubation or mechanical ventilation

• therapeutic bronchoscopy (foreign body removal, bronchial toilet, or stenting), discharge within 24 h of FOB

• surgical or diagnostic procedures within 24 h of FOB.

Related Conditions & MeSH terms

• Postoperative Complications

Intervention

Other:
• local surface anesthesia
Airway anesthesia for Bronchoscopy

Device:
• Laryngeal tube

Locations

Country	Name	City	State
China	The Second Hospital of Dalian Medical University	Dalian	Liaoning

Sponsors (1)

Lead Sponsor	Collaborator
The Second Affiliated Hospital of Dalian Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Fever	Fever was defined as an axillary body temperature 37.3°C	48 hour