Ketamine and Changes of the Short Portable Mental Status Questionnaire — SPMSQ-E  

Postoperative Cognitive Dysfunction Clinical Trial

Official title: Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.

Status Completed

Clinical Trial Summary

• Cognitive changes are related to aging, affecting the performance of older patients in the solution of problems and the execution of tasks.

This phenomenon has been observed as a decline of neurophysiological domains, especially memory, and the velocity of thought.

• Anesthesia and surgery performed contributes to its development then, is named post-operative cognitive dysfunction (POCD). The incidence varies due to conditions of:

1. Anesthesia and surgery.

2. The time elapsed after surgery.

3. The population studied, and the type of cognitive test employed.

• The aim of this study is to evaluate the changes around the Short Portable Mental Status Questionnaire (SPMSQ-E) after ketamine administration on ophthalmic surgery on the common conditions of geriatric patients, —comorbid and settings as minor surgery—.

Clinical Trial Description

Participants will be patients programmed for a vitrectomy or cataract surgery involving a retrobulbar block, to be carried out with a local anesthesia.

• Administration of ketamine will be suspended during the study for any cause considered as a risk to the patient according to the judgment of the researchers. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

• Cognition Disorders
• Postoperative Cognitive Dysfunction

• NCT number: NCT02049411
• Study type: Interventional
• Source: Instituto Mexicano del Seguro Social
• Status: Completed
• Phase: Phase 2
• Start date: June 2013
• Completion date: May 2014