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Post-operative Pain clinical trials

View clinical trials related to Post-operative Pain.

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NCT ID: NCT05361824 Completed - Clinical trials for Coronary Artery Disease

Ketorolac-an Option for Post Operative Pain Management After Elective Cardiac Surgery.

KOPAC
Start date: January 1, 2021
Phase: Phase 4
Study type: Interventional

OBJECTIVE: The purpose of this study was to compare the efficacy of Ketorolac versus Paracetamol as an adjunct to Nalbuphine in the management of post-operative pain following elective cardiac surgery. STUDY DESIGN: Randomized (single-blind) control trial. SAMPLING TECHNIQUE: Computer generated, randomized selection of patients with 50% probability of assignment into either group. PLACE AND STUDY DURATION: (single center) SICU at the National Institute of Cardiovascular Diseases Hospital, Karachi over a period of six months, from January 1, 2021 up to June 30, 2021. METHODS: Sixty patients (30 in each group) were randomly assigned to receive either Paracetamol (control) or Ketorolac (treatment), along with the usual Nalbuphine infusion, over the first 48 hours postoperatively. The control group received injection Paracetamol 1gm six hourly, whereas treatment group received injection Ketorolac 30mg eight hourly. PRIMARY OUTCOME: The VAS (pain score) was evaluated at 6, 12, 18 and 24 hours post-extubation and a score of 4 or less was taken as a cut-off for adequate pain control. SECONDARY OUTCOMES: The time taken to extubation postoperatively. The total dose of Nalbuphine administered to each patient and total chest tube drainage recorded over 48 hours postoperatively.

NCT ID: NCT05341323 Completed - Post Operative Pain Clinical Trials

Peri Tonsillar Infiltration of Ketamine or Bupivacaine for Post Tonsillectomy Analgesia

Start date: April 2, 2022
Phase: Phase 4
Study type: Interventional

Comparison between the analgesic effect of local infiltration of either Bupivacaine or ketamine in the peritonsillar area before the incision of tonsillectomy to achieve postoperative analgesia

NCT ID: NCT05331781 Completed - Post Operative Pain Clinical Trials

Ultrasound-Guided TAP Block and Spinal Morphine for Pain Relief After Caesarean Section

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

This interventional double-blind randomized controlled study was carried out on 60 cases underwent elective caesarean section delivery, they were divided into 2 groups; patients were randomly allocated into two equal groups; Group M: received intrathecal 150 microgram morphine in a 0.5 ml volume, mixed with 10 mg of hyperbaric bupivacaine 0.5 % in a 2 ml volume (total volume 2.5 ml). Group B: received intrathecal 10 mg hyperbaric bupivacaine 0.5% 2ml volume + 0.5 saline (Total volume 3ml) and at the end of surgery patient received bilateral TAP block with 20 ml volume of 0.25% bupivacaine on each side.

NCT ID: NCT05320783 Completed - Post Operative Pain Clinical Trials

Effect on Music Therapy on Quality of Recovery After Gynecological Laparoscopy

Start date: December 16, 2019
Phase: N/A
Study type: Interventional

In the present study, we intended to evaluate the effect of music intervention on postoperative pain, nausea, and comprehensive recovery quality in patients undergoing gynecological laparoscopic surgery.

NCT ID: NCT05317312 Completed - Pain Clinical Trials

Study of MR-107A-02 in the Treatment of Post Surgical Dental Pain.

Start date: March 31, 2022
Phase: Phase 2
Study type: Interventional

MR-107A-02 is being studied to investigate its efficacy, safety and dose-response after dental surgery.

NCT ID: NCT05310266 Completed - Surgery Clinical Trials

Transversus Abdominis Plane Block Versus Quadratus Lumborum Block for Pain Management in Laparoscopic Appendectomy

Start date: April 6, 2020
Phase: N/A
Study type: Interventional

Laparoscopic appendectomy causes postoperative pain. The primary objective of this prospective randomized controlled study is to compare the effect of ultrasound (US)-guided quadratus lumborum block (QLB) on 24-hour cumulative opioid requirements with transversus abdominis plane (TAP) block.

NCT ID: NCT05306535 Completed - Post Operative Pain Clinical Trials

Effect of Occlusal Reduction on Relief of Pain and Sensitivity to Percussion in Patients With Irreversible Pulpitis

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

One of the most important aspects of endodontic practice is to abate pain during and post root canal treatment. An endodontist by all means should provide a painless endodontic treatment to their patients. This study is carried out to determine the effect of occlusal reduction on relief of pain and percussion in patients with irreversible pulpitis and symptomatic apical periodontitis treated in a single visit root canal treatment. Pain will be assessed preoperatively and then post operatively after completion of the root canal at 6 hours, 12 hours, 24 hours, 48 hours and 72 hours following obturation of root canal.

NCT ID: NCT05300854 Completed - Post Operative Pain Clinical Trials

Serratus Block Versus Paravertebral Block for Post Thoracotomy Pain Relief

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This double-blinded, randomized controlled study was done on 60 patients older than 18 years undergoing thoracotomy. Patients were allocated into two equal groups (30 patients each). Group S: Standard anesthesia in addition to SPB. II. Group P: Standard anesthesia in addition to PVB.

NCT ID: NCT05299788 Completed - Pain, Acute Clinical Trials

Post-thoracotomy Pain Management With Active External Warming and Ice Application

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption. The research is a quasi-experimental design with control and study groups.

NCT ID: NCT05284695 Completed - Clinical trials for Bariatric Surgery Candidate

THE EFFICIENCY OF FASCIAL PLANE BLOCKS IN BARIATRIC SURGERY

Start date: January 1, 2019
Phase:
Study type: Observational

Bariatric surgery effectively produces weight loss and reduces obesity-related comorbidities. Although it is mostly performed with minimally invasive techniques, the patients may still suffer from moderate-to-severe pain immediately after surgery [1]. Opioids remain the first choice for multimodal analgesia in the treatment of postoperative pain. Providing analgesia after bariatric surgery might be challenging due to a high prevalence of obstructive sleep apnea syndrome and the increased sensitivity to respiratory depression triggered by opioid overuse after surgeryThe most common plane block techniques utilized during laparoscopic bariatric surgery are transversus abdominis plane block (TAP), rectus sheath block (RB), the erector spinae plane block (ESPB) and the external oblique intercostal block (EOI). In this study, we have evaluated the auxiliary benefit of these various techniques in reduction of the postoperative in bariatric surgery. patients who had laparoscopic bariatric surgery at VKV American Hospital between January 2019 and December 2021 were reviewed retrospectively.