Adductor Canal Nerve Block Following Total Knee Arthroplasty

Post-op Pain Clinical Trial

Official title:

Adductor Canal Nerve Block Following Total Knee Arthroplasty: A Randomized, Prospective Study Comparing High vs. Low Volume Bolus of 0.33% Ropivacaine

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT01939379
• Other study ID #: 5130183
• Status: Withdrawn
• Phase: N/A
• Start date: September 2013
• Est. completion date: July 25, 2017

Study information

• Verified date: April 2021
• Source: Loma Linda University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is that an adductor canal nerve block (putting numbing medicine near the nerve) has been shown to produce excellent pain relief with less pain medication use after knee replacement surgery.The investigators will be comparing the amount of pain relief following knee replacement surgery when you have a nerve block in place. There will be approximately 66 subjects participating in this study. After surgery subjects will receive numbing medication every 6 hours for 48 hours. Subjects will also receive a morphine PCA (patient controlled analgesia) after surgery and pain medication by mouth every 4 hours around the clock with the option to receive more pain medication if needed. Subjects will participate in the study up to 3 days.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: July 25, 2017
• Est. primary completion date: July 25, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 99 Years

Eligibility

Inclusion Criteria:

1. Is the subject undergoing primary unilateral total knee arthroplasty?

2. Is the subject 18 to 99 years of age?

3. Is the subject ASA class 1, 2, or 3?

4. Does the subject have a BMI less than 35?

5. Can the subject consent in the English language?

Exclusion Criteria:

1. Does subject have an allergy to drugs used in this study;

2. Does subject have a daily intake of opiate medications that are considered stronger than hydrocodone?

3. Does subject have a history of alcohol or drug abuse

4. Has subject had a previous total knee arthroplasty?

5. Has subject had any neurologic deficits in the lower extremity being studied?

Related Conditions & MeSH terms

• Pain, Postoperative
• Post-op Pain

Intervention

Drug:
• Morphine PCA started at the end of surgery, 1 Percocet 1/325mg every 4 hours; may receive a second Percocet if needed.

• For the 30ml ropivacaine the intervention would be the subject can request extra pain medication which would be Percocet and/or morphine PCA.

Locations

Country	Name	City	State
United States	Loma Linda University Medical Center East Campus Hospital	Loma Linda	California

Sponsors (1)

Lead Sponsor	Collaborator
Loma Linda University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Total Opiate pain medication	At the end of the 48 hours period the total opiate pain medication taken will be collected and used for comparison as our primary outcome	The total amount of opiate pain medication will be recorded at 6 hour intervals for 48 hours after surgery.
Secondary	Patient satisfaction with pain control	Secondary outcome measures will include demographic characteristics, pain scores, medication administration,patient satisfaction with pain control and any complications that may have arisen. We will also record the location of the adductor canal catheter on the final bolus dose.	We will look at the secondary outcome measure beginning every six hours for 48 hours after surgery