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Poisoning clinical trials

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NCT ID: NCT04050267 Completed - Clinical trials for Nitrous Oxide Poisoning

Effects of Low Concentrations of Nitrous Oxide

Start date: April 25, 2019
Phase: N/A
Study type: Interventional

The aim of the study is to test the effects of low concentrations of nitrous oxide on cognitive functions and reaction time in human.

NCT ID: NCT04036708 Completed - Malnutrition Clinical Trials

Caregiver Training to Prevent Konzo Disease in Children in Democratic Republic of Congo (DRC)

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The proposed research adapted the caregiver training and child neurodevelopmental assessment capacity that the PI previously built in Uganda beginning in 2008, to a community-based intervention model for the prevention of konzo in the Democratic Republic of Congo.

NCT ID: NCT03953248 Completed - Toxicity Clinical Trials

L-Carnitine as an Adjuvant Treatment in Acute Phosphide Poisoning (LC)

Start date: January 2016
Phase: Early Phase 1
Study type: Interventional

The aim of this study was to evaluate efficacy and safety of Alpha Lipoic Acid(ALA) as an adjuvant in the management of patients with acute phosphide poisoning.

NCT ID: NCT03926494 Completed - Coma Clinical Trials

Carbon Monoxide-induced Coma: Prognostic Factors

Coma-CO
Start date: May 1, 2019
Phase:
Study type: Observational

The primary objective of the study is to determine prognostic factors for hospital-mortality following carbon monoxide (CO)-induced coma. The secondary objective is to determine prognostic factors of CO related cognitive sequelae, at the time of hospital discharge.

NCT ID: NCT03925025 Active, not recruiting - Pesticide Poisoning Clinical Trials

Effectiveness of Calcium Channel Blockade for OP and Carbamate Pesticide Poisoning

CCBOC
Start date: June 11, 2020
Phase: Phase 3
Study type: Interventional

This study evaluates whether the addition of intravenous magnesium sulphate or nimodipine to standard therapy (supportive care plus for all patients atropine and, for OP insecticide poisoned patients, pralidoxime) benefits patients after acute anticholinesterase self-poisoning with OP or carbamate insecticides.

NCT ID: NCT03894306 Withdrawn - Poisoning Clinical Trials

Understanding How Medication is Stored in the Home

Start date: June 2021
Phase:
Study type: Observational

The goal of this study is to increase safe medication storage practices in homes with young children in order to prevent unintentional childhood poisonings. As a step toward meeting this goal, this study aims to determine if an intervention to promote safe storage to patients who have young children in their home, including provision of a lock box or lock bag along with brief counseling versus brief counseling alone, results in 1) increased locked storage (and overall safe medication storage practices) of high-risk prescription medications in the home; 2) increased safe medication storage practices of other medications in the home; and 3) improved safe medication storage related knowledge and attitudes.

NCT ID: NCT03893721 Not yet recruiting - Malnutrition, Child Clinical Trials

Effect of Chronic Arsenic Exposure on Malnutrition of Under Five Children

Start date: June 2019
Phase:
Study type: Observational

Early life malnutrition is associated with later life health problems, Particularly Stunting, which is a height-for-age Z score less than -2 standard deviation of World Health Organization median.Underweight is weight-for-age Z score less than -2 standard deviation of World Health Organization median. Wasting is weight -for- height Z score less than -2 standard deviation of World Health Organization median.

NCT ID: NCT03879356 Completed - Clinical trials for Using New Protocol to Prove the Role of N-acetyl Cysteine and Adequate Supportive Measures in Aluminum Phosphide Poisoning

Supportive Measures in Treatment of Aluminum Phosphide Poisoning

Start date: January 1, 2016
Phase: Phase 4
Study type: Interventional

Aluminum phosphide poisoning (ALP) is a global public health problem, and self-poisoning accounts for one-third of the world's suicide rate. In fact, in some parts of developing countries, pesticide poisoning causes more deaths than infection. ALP is very common in our government and the prognosis of the cases is usually so bad. Toxicity by ALP is caused by the liberation of phosphine gas, which causes cell hypoxia due to inhibition of oxidative phosphorylation leading to circulatory failure.

NCT ID: NCT03826537 Completed - Tutin Poisoning Clinical Trials

A Study of How Tutin and Hyenanchin, Two Toxins Found in Honey, Are Absorbed and Processed by the Body

Start date: January 2012
Phase: N/A
Study type: Interventional

Honey available in New Zeland can contain the toxins tutin and hyenanchin. Tutin is produced by several plants native to New Zealand. Bees collect honeydew contaminated with tutin and hyenanchin for honey production. Honey contaminated with high levels of tutin has caused cases of poisoning in New Zealand since the 1800s, with the most recent outbreak in 2008. The study aims to find out how tutin and hyenanchin are absorbed and processed by the body. This information will help the FSANZ give guidance on acceptable levels of tutin and hyenanchin in honey. About 6 healthy men will each take a single dose of honey containing known concentrations of tutin and hyenanchin. This dose level is similar to what someone who eats a lot of honey would have, if the honey contained the maximum level of tutin allowed under the Food Standards Code. Blood tests to measure tutin and hyenanchin levels will be taken at certain times after dosing, and any side effects will be recorded.

NCT ID: NCT03818841 Recruiting - Clinical trials for Carbon Monoxide Poisoning

The Role of High-flow Nasal Cannula Therapy in the Treatment of Acute Carbon Monoxide Poisoning

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The aim of the study is to test whether oxygen therapy delivered through high-flow nasal cannula devices in patients admitted to the emergency department for acute carbon monoxide poisoning is superior to the non-rebreathing oxygen face mask therapy with a 15 L/minute oxygen flow (currently the first-line therapy), in terms of reduction of carboxyhemoglobin (COHb) concentration and delayed neurological sequelae incidence.