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Poisoning clinical trials

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NCT ID: NCT02860455 Recruiting - Clinical trials for Carbon Monoxide Poisoning

Role of Pulse Co-oximetry for Detecting Carbon Monoxide Poisoning in the Prehospital Emergency Medical Service Setting

CO-OX
Start date: February 2012
Phase: N/A
Study type: Interventional

The RAD-57 pulse CO-oximeter is a lightweight device allowing non-invasive measurement of blood carboxyhemoglobin. Previous studies comparing RAD-57 measurements (SpCO) to standard laboratory blood gas analysis (COHb) have reported contradictory results. the RAD-57 pulse CO-oximeter could be useful as a first-line screening test for acute CO poisoning, enabling rapid detection and management of patients with suspected CO poisoning in the prehospital emergency setting This study assesses the diagnostic value of pulse CO-oximetry, comparing SpCO to standard laboratory blood measurement for prehospital management of patients with suspected carbon monoxide (CO) poisoning.

NCT ID: NCT02838303 Completed - Clinical trials for Organophosphate Poisoning

The Use of Self-reported Symptoms as a Proxy for Acute Organophosphate Poisoning Among Nepali Farmers

Start date: September 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate self-reported symptoms as a proxy for acute organophosphate poisoning by examining self-reported acute organophosphate poisoning symptoms and PchE activity in response to occupational acute organophosphate exposure among farmers in Nepal.

NCT ID: NCT02580760 Completed - Clinical trials for Injection Site Extravasation

Transgender, Silicone and Blood Smear

TSBS
Start date: July 2015
Phase: N/A
Study type: Observational

This cross-sectional monocentric study will describe transgender men transitioning into women and who had cosmetic silicone injection. The principal objective is to estimate the prevalence of Transgender with circulating monocytes containing silicone vacuoles in blood smears among Male to Female Transgender population with a history of cosmetic silicon injections. The secondary objectives are to describe the transgender population, to describe the quantity of silicone in vacuoles of circulating monocytes, and the association between dermatological complications (inflammatory and not inflammatory) and several clinical and biological characteristics (HIV status, level of immunosuppression, inflammatory syndrome, quantity of silicone which was injected , silicone quantity in blood smears).

NCT ID: NCT02553070 Completed - Poisoning Clinical Trials

Health Professions Students and Faculty Perceptions of Poisoning Severity

Start date: September 2015
Phase: N/A
Study type: Observational

Inaccurate perceptions of the severity of an exposure may result in unnecessary visits to the Emergency Department or Health Care Facility which can result in crowding of Emergency Departments, unnecessary utilization of valuable health care resources, unnecessary treatments, and or mistakes / errors resulting in harm to the patient. Inaccurate perceptions about the severity of an exposure can result in delays in proper evaluation and treatment resulting in harm or in some cases death of the patient.

NCT ID: NCT02486289 Completed - Mercury Poisoning Clinical Trials

Pilot Proof of Concept Study of NBMI Treatment of Mercury Intoxication

NBMI
Start date: August 2015
Phase: Phase 2
Study type: Interventional

A randomized, placebo controlled, double blind proof of concept study of NBMI in treatment of mercury intoxication.

NCT ID: NCT02483650 Enrolling by invitation - Clinical trials for Carbon Monoxide Poisoning

Hyperbaric Oxygen Therapy Registry

HBOTR
Start date: January 2005
Phase:
Study type: Observational [Patient Registry]

The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of "Stage 2 of Meaningful Use," including data provided to meet PQRS requirements via the registry's QCDR mission. Goals include understanding the value of HBOT among patients treated for a variety of conditions in relation to the frequency and severity of HBOT side effects. While randomized, controlled trials can establish the efficacy of treatments like HBOT, because they routinely exclude patients with co-morbid conditions common to those patients seen in usual clinical practice, the results of RCTs are usually non-generalizable. Real world data can be used to better understand the effectiveness of HBOT among typical patients, as well as the risks associated with treatment.

NCT ID: NCT02444858 Recruiting - Lung Injury Clinical Trials

Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Paraquat Poisoning Induced Lung Injury

UCMSC-PQLI
Start date: May 2015
Phase: Phase 1/Phase 2
Study type: Interventional

Phase I-II Clinical Trial-Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with paraquat poisoning induced lung injury, randomized,single blind, controlled prospective study.

NCT ID: NCT02429921 Completed - Arsenic Poisoning Clinical Trials

High-selenium Lentils Versus Arsenic Toxicity

Start date: October 2015
Phase: N/A
Study type: Interventional

About 45 million people in Bangladesh are chronically exposed to unacceptable levels of arsenic in their drinking water. Chronic arsenic poisoning leads to cancers, and vascular diseases. This dietary trial intends to test the potential of high-selenium lentils, consumed as lentil soup, in reducing the arsenic body burden in an exposed Bangladeshi population, and in improving the overall health status. Arsenic-exposed families will be assigned to one of two groups. One group will eat lentils (50g/person/day) that are naturally high in selenium, the other group will receive lentils with low selenium content. This 6 months trial is randomized and double-blinded.

NCT ID: NCT02421029 Withdrawn - Clinical trials for Heavy Metal Toxicity

Prolonged Gadolinium Retention After MRI Imaging

Start date: July 2017
Phase: Phase 4
Study type: Interventional

The researchers propose to investigate the prevalence of gadolinium in the urine of patients with a prior gadolinium-enhanced MRI before and after a edetate calcium disodium challenge. Moreover, will investigate if there is any correlation of gadolinium urine levels with levels of endogenous (e.g zinc) and xenobiotic metals.

NCT ID: NCT02415712 Completed - Clinical trials for Ethylene Glycol Poisoning, Methanol Poisoning

Specified Drug-use Survey of Fomepizole Intravenous Infusion (All-case Surveillance)

Start date: January 27, 2015
Phase:
Study type: Observational

The objective of this survey is to evaluate the safety and efficacy of fomepizole intravenous infusion in Japanese patients with ethylene glycol and methanol poisonings in daily medical practice.