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Pneumonia clinical trials

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NCT ID: NCT05005091 Completed - Clinical trials for Non Small Cell Lung Cancer

Effect of Preoperative Oral Carbohydrate Administration in Thoracic Surgery Patients

oralcarbohydra
Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Preoperative carbohydrate loading has been shown to reduce pre-operative discomfort and postoperative nausea and vomiting. There is no need for prolonged preoperative fasting of the patients, but the traditional approach still continues especially in thoracic surgery patients. For this purpose, we aimed to evaluate the effect of preoperative carbohydrate loading on postoperative morbidity in the patients.

NCT ID: NCT04998799 Completed - Thrombosis Clinical Trials

Practice Variation on Antithrombotics in COVID-19

Start date: October 1, 2021
Phase:
Study type: Observational

Evidence suggests coronavirus disease 2019 (COVID-19) is associated with an increased incidence of thromboembolic manifestations. Various guidelines on managing antithrombotics in COVID-19 either provided conflicting guidance or unclear recommendations for post-discharge thromboprophylaxis. The investigators aim to collect the current practices in India among physicians on antithrombotic therapy for hospitalised patients with COVID-19 and after discharge from the hospital.

NCT ID: NCT04996693 Completed - Lung Cancer Clinical Trials

On Dose Efficiency of Modern CT-scanners in Chest Scans

Start date: October 7, 2021
Phase: N/A
Study type: Interventional

CT scans of the chest / thorax are of great importance both in the initial diagnosis and in the follow-up of pulmonary or thoracic diseases. As an example, CT angiography of the pulmonary arteries (CTPA) is worldwide considered to be gold standard test in patients with a suspicion for pulmonary embolism. The aim of this study is to measure and compare dose efficiency of modern CT scanners for unenhanced and contrast-enhanced scan protocols of the chest/thorax. Patients who are referred for a CT of the chest/thorax will be randomly assigned to one of the three CT scanners currently in use at our institution.

NCT ID: NCT04977011 Completed - Stroke Clinical Trials

Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient

Start date: January 2, 2019
Phase: N/A
Study type: Interventional

Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning. The effectiveness of music intervention in reducing anxiety of patients in Intensive Care Unit (ICU) is still unknown. The purpose of this study was to examine the effectiveness of music intervention on anxiety, agitation, sleep quality and physiological parameters on patients in ICU. This study was conducted from January to June 2019. A total of 196 hospitalized ICU patients were divided into two groups. Subjects in experimental group received 30 minutes music intervention for 3 days on bedside whereas subjects in control group received routine care only. The primary outcome was anxiety. Agitation Sedation Scale, sleep quality and physical parameters were selected to collect as secondary outcomes.There was no significant difference between the groups at baseline. The results of this study support that music can reduce anxiety and agitation levels in ICU's patient. Nurses can incorporate this intervention into the daily care in order to reduce the discomfort of patients.

NCT ID: NCT04973488 Completed - Clinical trials for Acute Respiratory Distress Syndrome

Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 Patients

Start date: July 25, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

Therapeutic plasma exchange (TPE) has been proposed as a rescue therapy in critically ill COVID-19 patients. The aim of this study is to determine whether combining TPE with convalescent plasma (CVP) transfusion early during the intensive care unit (ICU) stay, improves survival among this heterogeneous population.

NCT ID: NCT04966026 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Clinical Characteristics and Outcome of Patients With COPD With Pneumonia

Start date: March 1, 2017
Phase:
Study type: Observational

To identify the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) combined with community-acquired pneumonia (CAP) and the factors influencing clinical transition.

NCT ID: NCT04963764 Completed - Pneumonia Clinical Trials

Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia

PRAPP
Start date: October 18, 2021
Phase: Early Phase 1
Study type: Interventional

This pilot study will evaluate study processes and feasibility of a future large-scale clinical trial that proposes to test whether low-risk children managed as outpatients with community-acquired pneumonia (CAP) and procalcitonin (PCT) levels <0.25 ng/mL treated with placebo have a similar clinical response to those treated with antibiotics and fewer adverse effects.

NCT ID: NCT04959344 Completed - Clinical trials for Klebsiella Pneumoniae Infection

Safety and Immunogenicity of a Klebsiella Pneumoniae Tetravalent Bioconjugate Vaccine (Kleb4V)

Start date: July 5, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

In this study, the tetravalent bioconjugate candidate vaccine Kleb4V will be tested to obtain first-time-in-human (FTIH) data on its safety and immunogenicity in healthy adults.

NCT ID: NCT04954118 Completed - COVID-19 Pneumonia Clinical Trials

A Different Use of The Aerosol Box in COVID-19 Patients; Internal Jugular Vein Cannulation

Start date: March 20, 2020
Phase: N/A
Study type: Interventional

During the COVID-19 pandemic, health employees are at high risk of infection. This study aimed to determine experiences with an aerosol box (AB), used with the aim of preventing contamination by droplets during internal jugular vein cannulation which requires close contact with COVID-19 patients, and the necessity to use this device.

NCT ID: NCT04953247 Completed - COVID-19 Pneumonia Clinical Trials

Use of Compromised Lung Volume in Monitoring Usage of Steroid Therapy on Severe COVID-19

Start date: February 7, 2020
Phase:
Study type: Observational

Since December 2019, the outbreak of coronavirus disease 2019 (COVID-19) has become a public health emergency of international concern. Although corticosteroid therapy represents a milestone in the management of COVID-19, many questions remain unanswered. The optimal type of corticosteroids, timing of initiation, dose, mode of administration, duration, and dose tapering are still unclear. An approach to resolve these issues is to develop accurate tools to assess or monitor the progression of COVID-19 during the corticosteroid therapy process. Quantitative computed tomography (QCT) analysis may serve as a tool for assessing the severity of COVID-19 and for monitoring its progress. However, the effect of steroids on quantitative chest CT parameters during the treatment process remains unknown. In this retrospectively study, we aimed to assess the association between steroid administration and QCT variables in a longitudinal cohort with COVID-19