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Plaque Psoriasis clinical trials

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NCT ID: NCT05364554 Completed - Plaque Psoriasis Clinical Trials

A Long-term Extension Study of JNJ-77242113 in Participants With Moderate-to-Severe Plaque Psoriasis

FRONTIER 2
Start date: June 10, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate long-term clinical response of JNJ-77242113 treatment in participants with moderate-to-severe plaque psoriasis.

NCT ID: NCT05357755 Completed - Plaque Psoriasis Clinical Trials

A Study of JNJ-77242113 for the Treatment of Moderate-to-Severe Plaque Psoriasis

SUMMIT
Start date: June 13, 2022
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the efficacy of an oral tablet formulation of JNJ-77242113 compared with placebo in participants with moderate-to-severe plaque psoriasis.

NCT ID: NCT05344482 Completed - Plaque Psoriasis Clinical Trials

Evaluation of the Effectiveness of Secukinumab in Patients With Moderate to Severe Plaque Psoriasis

Start date: July 9, 2020
Phase:
Study type: Observational

This study was a real-life study which was based on secondary data collection from the electronic or paper medical records from the Dermatology Clinics of the 14 University, Training & Research Hospitals in Turkey. Data were extracted between 02 September 2020 and 29 April 2021.

NCT ID: NCT05332704 Suspended - Plaque Psoriasis Clinical Trials

Safety, Tolerability, PK, PD and Preliminary Efficacy of ONO-4685

Start date: March 25, 2022
Phase: Phase 1
Study type: Interventional

This is an early phase study to assess the safety and tolerability of ONO-4685 in patients with psoriasis. In addition, the study will assess how the drug is distributed and eliminated by the body (pharmacokinetics) and how the drug affects the body (pharmacodynamics). This will be done by measuring the amount of drug in the blood and measuring other markers in the body that might have been affected by ONO-4685. The study will also look at preliminary information on whether ONO-4685 might be effective in treating psoriasis. The study will be split into three parts. Part A will assess a single dose of ONO-4685 in small groups of patients, each group planned to receive a higher dose than the last group. In Part B and C, patients will receive multiple doses of ONO-4685 over a period of 4 weeks.

NCT ID: NCT05330936 Completed - Plaque Psoriasis Clinical Trials

Comparison of Cyanocobalamin in Avocado Oil Cream With Steroid Combination Ointment

Start date: January 1, 2021
Phase: Early Phase 1
Study type: Interventional

A randomized clinical trial with two groups. Group A Group B Group A is being treated with conventional Steroid combination ointment for the treatment of chronic Plaque Psoriasis. Group B is being treated with Cyanocobalamin in Avocado Oil cream for the treatment of chronic Plaque Psoriasis. Each group having 45 patients.

NCT ID: NCT05282771 Completed - Plaque Psoriasis Clinical Trials

A Study Comparing Halobetasol Propionate and Tazarotene Topical Lotion 0.01%/0.045% to Duobrii® Lotion (Halobetasol Propionate and Tazarotene Lotion), 0.01%/0.045% (Reference Listed Drug) in the Treatment of Moderate to Severe Plaque Psoriasis.

Start date: April 16, 2021
Phase: Early Phase 1
Study type: Interventional

To evaluate the therapeutic equivalence and safety of halobetasol propionate and tazarotene topical lotion 0.01%/0.045% (Taro Pharmaceuticals U.S.A., Inc.) and Duobrii® Lotion (halobetasol and tazarotene lotion), 0.01%/0.045% (Reference Listed Drug) in the treatment of moderate to severe plaque psoriasis.

NCT ID: NCT05272150 Active, not recruiting - Plaque Psoriasis Clinical Trials

Study of Guselkumab in Skin of Color Participants With Moderate-to-severe Plaque and/or Scalp Psoriasis

VISIBLE
Start date: July 13, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy of guselkumab treatment versus placebo in skin of color participants with predominant moderate-to-severe body psoriasis or predominant moderate-to-severe scalp psoriasis by assessing improvements in the signs and symptoms of psoriasis.

NCT ID: NCT05268016 Completed - Plaque Psoriasis Clinical Trials

Efficacy and Safety of ME3183 in Subjects With Moderate to Severe Plaque Psoriasis

Start date: March 24, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of ME3183 administered orally for moderate to severe plaque psoriasis in adults.

NCT ID: NCT05223868 Completed - Plaque Psoriasis Clinical Trials

A Study of JNJ-77242113 in Participants With Moderate-to-severe Plaque Psoriasis

FRONTIER 1
Start date: February 3, 2022
Phase: Phase 2
Study type: Interventional

Th purpose of the study is to evaluate the dose response of JNJ-77242113 in efficacy at Week 16 in participants with moderate-to-severe plaque psoriasis.

NCT ID: NCT05203315 Recruiting - Plaque Psoriasis Clinical Trials

Investigator Initiated Trial to Study Duobrii® Lotion in the Treatment of Mild Plaque Psoriasis in Adults

Start date: January 13, 2022
Phase: Phase 3
Study type: Interventional

This study seeks to evaluate the safety, tolerability, and efficacy of topical Duobrii® Lotion in adult subjects with mild plaque psoriasis.