Remote Ischemic Conditioning for Parkinson's Disease

Status Completed

Clinical Trial Summary

The purpose is to evaluate feasibility and efficacy of Remote Ischemic Conditioning(RIC) as adjuvant therapy for Parkinson's Disease(PD). Sixty patients will be randomized into 2groups: RIC group receiving Remote Ischemic Conditioning except conventional therapy（n=30）and control group with conventional therapy (n=30).

Clinical Trial Description

Remote ischaemic conditioning (RIC) is a procedure whereby ischaemia is induced to a limb for short periods of time by inflating pressure cuffs around arms to above systolic pressures (mmHg). This procedure induce neurohormonal, systemic or vascular changes in the body. Such changes often result in improved collateralisation of blood supply to various areas of the body, as well as improved efficiencies of cellular metabolism. RIC has been shown to improve outcomes in patients with heart attacks, strokes, but is not investigated for PD. We argue that RIC may exert neuroprotective effect on PD due to its multiple mechanisms. The aim of the study is to evaluate the impact of RIC on long term outcomes in patients with PD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04327687
Study type	Interventional
Source	General Hospital of Shenyang Military Region
Contact
Status	Completed
Phase	N/A
Start date	August 18, 2020
Completion date	November 30, 2022

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