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Clinical Trial Summary

This study is a single-site, double-blinded, randomized clinical trial designed to elucidate mechanism(s) of action for symptomatic benefits observed in Parkinson's disease (PD)


Clinical Trial Description

Patients treating twice daily using a non-invasive brainstem modulation device. Study participants will self-administer treatments in the home setting over a period of 12 weeks. Changes in cerebral blood flow perfusion, cerebrovascular reactivity and functional connectivity between the pre-treatment baseline and the end of the treatment period will be monitored and compared to changes in validated standardized clinical measures of motor and non-motor symptoms in PD. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04598828
Study type Interventional
Source Wake Forest University Health Sciences
Contact Christopher T Whitlow, MD, PhD
Phone 336-713-8793
Email cwhitlow@wakehealth.edu
Status Recruiting
Phase N/A
Start date July 6, 2021
Completion date June 2025

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