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Paresis clinical trials

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NCT ID: NCT04672057 Completed - Hemiparesis Clinical Trials

Investigation of the Spatio-temporal Gait Parameters in Individuals With Hemiparesis: Effect of Lateralization

Start date: July 8, 2017
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the effect of lateralization on the spatio-temporal characteristics of gait in individuals with hemiparesis.

NCT ID: NCT04652934 Completed - Clinical trials for Acquired Brain Injury

Effectiveness of the Neural Mobilization on Upper Limb Functionality in Patients With Acquired Brain Injury

Start date: January 26, 2022
Phase: N/A
Study type: Interventional

The main objective: To determine changes in physiological and structural properties of upper limb muscles with spasticity in patients with acquired brain injury after applying neural mobilization improving their functional performance, their participation in society and quality of life. Hypothesis: Peripheral nerve mobilizations performed with neurodynamic techniques in upper limb in patients with acquired brain injury, generate changes at structural and physiological level, favoring the performance of daily life activities and improving the quality of life.

NCT ID: NCT04595045 Completed - Multiple Sclerosis Clinical Trials

Botulinum Toxin in Patients With Spastic Lower Limb Paresis Associated With Multiple Sclerosis

Start date: January 24, 2019
Phase: Phase 3
Study type: Interventional

Spastic paraparesis is one of the most disabling functional deficits in the population with multiple sclerosis between 18 and 80 years of age and at any functional level. Infiltration with Botulinum Toxin is a clinical practice that has been carried out for years with clinical evidence of improvement in the patient's walking patterns and quality of life. We assume that the infiltration of this product can generate a direct benefit in the walking ability of these patients and secondarily improve their quality of life.

NCT ID: NCT04554238 Completed - Cerebral Palsy Clinical Trials

Effectiveness of Armeo Spring Robotic Therapy in the Function of the Upper Limb of Children With Unilateral Spastic Cerebral Palsy Infiltrated With Botulinum Toxin

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Background: Unilateral spastic cerebral palsy (CP) generates an impact on daily activities, mainly due to the functional limitation of the affected upper limb. The use of technologies such as Armeo spring robotic therapy seeks to improve upper limb mobility through innovative and motivating training that facilitates movement. Objective: To assess the effectiveness of Armeo spring robotic therapy versus conventional occupational therapy regarding the changes in upper limb functionality of children with unilateral spastic CP infiltrated simultaneously with botulinum toxin A (BTA). Patients and methods: Randomized clinical trial of parallel groups, in children between 4 and 10 years of age diagnosed with unilateral spastic CP and infiltrates with BTA, who received treatment of conventional occupational therapy (group I) or Armeo spring robotic therapy (group II). The intervention consists of 15 sessions of 40 minutes for 5 weeks, 3 times a week. An initial evaluation is applied with QUEST, ABILHAND-Kids, and MACS, which are re-evaluated at 3 and 6 months. Hypothesis: Armeo spring robotic therapy will obtain better results than conventional occupational therapy in relation to the functionality of the upper limb at the level of manipulative function, quality of movement of the limb and the performance of daily activities. Expected results: The results of the QUEST and ABILHAND-Kids dimensions assessed before, after and at follow-up will be the primary outcome. The presence of adverse effects will correspond to secondary outcome. Benefit and limitations: Direct social contribution for patient's rehabilitation by using technology and a contribution to research to update scientific evidence. Possible limitations could be presence of adverse effects and poor adherence to treatment.

NCT ID: NCT04536987 Completed - Stroke Clinical Trials

Robot Therapy for Rehabilitation of Hand Movement After Stroke

HEXORR
Start date: October 4, 2012
Phase: Phase 2
Study type: Interventional

A study will be performed where individuals with chronic stroke will be randomly assigned to receive 2 different dosages of robotic hand therapy. One group will receive 12 sessions of robot-assisted repetitive movement practice in the HEXORR robot over a 4-5 week period. A second group will receive 24 sessions of HEXORR therapy over a 8-10 week period.

NCT ID: NCT04529343 Completed - Cerebral Palsy Clinical Trials

Virtual Reality Mediated Upper Extremity rehabilitationPatients With Cerebral Palsy

Start date: August 20, 2020
Phase: N/A
Study type: Interventional

Cerebral palsy (CP) refers to a group of permanent disorders that occur in the brain of the fetus or infant, which are non-progressive, cause movement and posture disorder along with activity limitation. The upper extremity is frequently affected in patients with CP. The prevalence of upper extremity involvement has been reported between 60-83% in different studies. Virtual reality applications have been increasing recently in the field of neurological rehabilitation. In this study, researchers aimed to investigate the effectiveness of virtual reality-mediated upper extremity rehabilitation in patients with hemiplegic cerebral palsy.

NCT ID: NCT04515407 Completed - Stroke Clinical Trials

Plantarflexor PAS - Stroke

PAS - Stroke
Start date: October 1, 2021
Phase: N/A
Study type: Interventional

The current project investigates a method called paired associative stimulation (PAS) which is known to influence nervous system function through a process called neuroplasticity. Here the investigators will target function of the ankle plantarflexor muscles because they are critically important to walking. The investigators will study adults who have walking dysfunction resulting from stroke. The study will test three ways of delivering PAS targeted towards brain-muscle connections serving the ankle plantarflexors. The overall goal is to improve functioning of the plantarflexors. The investigators believe that improving plantarflexor function will increase the likelihood of positive effects from gait retraining programs for people post-stroke. Participants will experience all three PAS methods in separate sessions. The investigators will compare differences in the size of these effects to identify the optimal method for delivery of PAS to the ankle plantarflexors. This study is a preliminary step to help us design a better clinical trial of combined PAS and gait retraining.

NCT ID: NCT04502290 Completed - Stroke Clinical Trials

Synchronized Brain and Hand Stimulation After Stroke

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Among the 795,000 individuals who sustain a stroke annually in the United States, 65% continue to experience moderate-to-severe impairments in one hand six months or more, which limits their ability to perform daily tasks. Currently there is dearth of understanding of the mechanisms of motor recovery after stroke. Understanding the mechanisms can potentially lead to the development of interventions to improve motor performance after stroke. The proposed study will examine how synchronously pairing brain and hand stimulation repeatedly affects the plasticity of the brain and motor performance after stroke. The knowledge gained from this study can be useful to develop interventions to improve hand movement after moderate-severe stroke.

NCT ID: NCT04498429 Completed - Clinical trials for Hemiplegia and/or Hemiparesis Following Stroke

Effect of Integrated Cueing on Functional Transfers in Chronic Stroke Survivors

EOIC
Start date: November 6, 2020
Phase: N/A
Study type: Interventional

Physical therapists frequently use manual cueing as a tool to improve movement quality in persons recovering from stroke but evidence to support its effectiveness is lacking. The purpose of this graduate student research study is to determine the immediate and carryover effects of an integrated verbal and manual facilitation approach used by physical therapists during sit to stand training on the midline alignment, muscle activation and quality of movement in chronic stroke survivors with hemiplegia.

NCT ID: NCT04423497 Completed - Hemiparesis Clinical Trials

ESTIMATION OF BALANCE STATUS IN HEMIPARETICS

Start date: July 31, 2016
Phase:
Study type: Observational

Although Balance Evaluation Systems Test(BESTest) is an important balance assessment tool to differentiate balance deficits, it is time consuming and tiring for hemiparetic patients. Using artificial neural networks(ANNs) to estimate balance status can be a practical and useful tool for clinicians. The aim of this study was to compare manual BESTest results and ANNs predictive results and to determine the highest contributions of BESTest sections by using ANNs predictive results of BESTest sections. 66 hemiparetic individuals were included in the study. Balance status was evaluated using the BESTest. 70%(n=46), of the dataset was used for learning, 15%(n=10) for evaluation, and 15%(n=10) for testing purposes in order to model ANNs. Multiple linear regression model(MLR) was used to compare with ANNs.