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Parasomnias clinical trials

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NCT ID: NCT02951689 Completed - Healthy Clinical Trials

Probiotics in Occupational Shift Workers

Start date: September 2016
Phase: N/A
Study type: Interventional

Purpose: To evaluate the influence of probiotic supplementation on body composition and other markers of health in occupational shift-workers. Participants: Healthy, overweight females (ages 22-55 yrs) who are employed on a shift-working schedule. Procedures (methods): In a randomized, placebo-controlled intervention, subjects will complete 3 different testing sessions (pre-screening, 1 baseline, 1 post-testing session) as well as a 6-week intervention period. Prescreening will include written informed consent, a health history questionnaire, baseline anthropometric measures, assessment of resting heart rate, and exercise protocol familiarization. Baseline testing will involve body composition, a fasted blood draw, mood surveys, and an exercise treadmill test. Subjects will be randomized to a treatment group (multi-strain probiotic or placebo) for 6 weeks of supplementation that includes 2 electronic contacts, followed by post-testing that will occur in the same fashion as baseline testing.

NCT ID: NCT02940912 Completed - Parkinson Disease Clinical Trials

Effect of Continuous Apomorphine During the Night on Sleep Disorders in Insomniac Patients With Parkinson's Disease

APOMORPHEE
Start date: January 31, 2017
Phase: Phase 4
Study type: Interventional

The purpose of the study is to demonstrate that continuous apomorphine treatment during the night compared with placebo improves sleep quality in insomniac patient with Parkinson's disease.

NCT ID: NCT02939586 Completed - Sleep Clinical Trials

The Effect of Haemodialysis in Sleep Apnoea

Start date: October 2016
Phase: N/A
Study type: Interventional

Sleep disturbance is a significant issue in people undergoing dialysis. More than 80% of haemodialysis patients complain of difficulty sleeping. Inadequate sleep can cause poor daytime function and increased risk of motor vehicle incidents. One of the common reasons for sleep disturbance in dialysis patients is sleep apnoea. Sleep apnoea involves pauses in breathing that occur during sleep. Each pause can last only a few seconds or minutes. Severe sleep apnoea reduces oxygen supply and increases risk of heart attack and stroke, which are the leading causes of death in dialysis patients. In this project, the investigators will examine how a change of dialysis treatment might improve sleep. This project will first identify patients at risk of sleep disturbance using surveys and a subsequent sleep study. The investigators will then test different dialysis models to see the effect of dialysis treatment on sleep apnoea. The aim is to find a dialysis model that works better for patients with sleep apnoea.

NCT ID: NCT02874261 Completed - Physical Activity Clinical Trials

Whole Body Periodic Acceleration on Activity and Sleep In Parkinson's Disease

Start date: May 2015
Phase: N/A
Study type: Interventional

Whole-body periodic acceleration (WBPA) is a new, non-invasive, and promising therapy for a diverse and growing list of disorders including cardiovascular disease. During WBPA, patients lie in the supine position on a bed that is capable of translating back and forth parallel to the ground, along the head-to-foot axis of the patient. Thus, this treatment is best described as a form of "passive exercise." The frequency of the translation (up to 180 cycles/minute; cpm) as well as the distance traveled (2-24mm) by the bed can be adjusted by the patient or health care professional. The science behind the therapeutic effects of WBPA still remains largely unknown. The investigators are observing how WBPA may impact on sleep and activity in individuals with Parkinson's disease.

NCT ID: NCT02797678 Completed - Sleep Clinical Trials

Feasibility, Effectiveness and Efficacy of the PowerSleep Device

Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of this study is test the effectiveness of the PowerSleep auditory stimulation device on sleep quality and daytime functioning in individuals who have insufficient sleep. The PowerSleep device is a non-invasive portable device designed to increase deep sleep, potentially reducing daytime sleepiness related to insufficient sleep. The device is meant to be worn while a person is sleeping. The device delivers soft audio tones (below 65dB (decibels)/ normal speaking voice) via headphones periodically throughout the night and records the electrical activity of the brain (electroencephalogram (EEG)). The device consists of a headband with 4 sensors on the forehead, one sensor behind the right ear, headphones covered by speaker foam over each ear, and a cable which connects the headband to an upper arm band. The armband contains the device electronics. The headband and the armband are connected via adjustable Velcro closure. This device has not been released for sale and is considered investigational. The study includes approximately 30 people from four study sites. It is anticipated that a total of up to 10 people will complete the study at this site. This study is designed to last up to 6 weeks.

NCT ID: NCT02775331 Completed - Sleep Disturbance Clinical Trials

The Use of Worktime Planning Tools in the Finnish Public Sector. A Quasi-experimental Study (PLANTOOLS)

PLANTOOLS
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

This study aims to investigate whether use of interactive worktime planning tools that support work-time control (possibilities to influence individual shift rosters, i.e., participatory rostering) and guide for health-supporting shift ergonomics will improve health and well-being among shift workers, especially among ageing employees. Effects of the worktime planning tools will be studied in a quasi-experimental design in the Finnish public sector. Health and well-being at baseline (2012-2015), will be compared to follow-up data in 2016-2019 based on questionnaire and pay-roll based objective working hour and sickness absence data among those who a) use an interactive self-rostering software with a shift ergonomics sub-tool, b) whose working hours are designed with a non-interactive shift planning software with the shift ergonomics sub-tool and c) whose working hours are designed with a non-interactive shift planning software without the shift ergonomics sub-tool.

NCT ID: NCT02761161 Completed - Depression Clinical Trials

Treatment of Sleep Disturbances in Trauma-affected Refugees

PTF5
Start date: March 2016
Phase: Phase 4
Study type: Interventional

The overall aim of this study is to examine the effects of sleep enhancing treatment in refugees with PTSD.

NCT ID: NCT02757079 Completed - Sleep Disorders Clinical Trials

Study of the Efficacy and Safety of NPC-15 for Sleep Disorders of Children With Neurodevelopmental Disorders

NPC-15-6
Start date: June 21, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy on sleep latency with electronic sleep diaries and the safety of NPC-15.

NCT ID: NCT02757066 Completed - Clinical trials for Autism Spectrum Disorder

Verification of the Efficacy of NPC-15 for Sleep Disorders of Children With Autism Spectrum Disorders

NPC-15-5
Start date: June 16, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to verify the efficacy of NPC-15 (melatonin 1 mg/d or 4 mg/d) versus placebo to sleep latency with electronic sleep diaries.

NCT ID: NCT02752139 Completed - Clinical trials for Sleep Disorders, Intrinsic

Cerebral Hemodynamics in Sleep Disorders

Start date: May 2016
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to determine the relationship between sleep disorders and cerebral hemodynamics.