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Panic Disorder clinical trials

View clinical trials related to Panic Disorder.

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NCT ID: NCT02756507 Completed - Clinical trials for Generalized Anxiety Disorder

Transdiagnostic REBT Prevention Program for Adolescents

Start date: June 2016
Phase: N/A
Study type: Interventional

Anxiety and depressive disorders are common in adolescents, however they are often unrecognized. Rational emotive behavioral therapy (REBT), a form of cognitive behavioral therapy (CBT) is efficient for children and adolescents. School settings are appropriate environments to deliver such interventions for vulnerable youths. Given youth's access and predilection to use technology, a video-based prevention program was developed. The present study aims to investigate the efficacy of a transdiagnostic REBT prevention program for internalizing symptoms in adolescents, implemented in a school setting. Classes from different Romanian public schools will be randomized in either intervention or wait list group.

NCT ID: NCT02739607 Recruiting - Depression Clinical Trials

Internet-delivered Transdiagnostic Intervention for Anxiety and Depression

iTAD
Start date: April 2016
Phase: N/A
Study type: Interventional

Objectives 1. To test the effectiveness and acceptability of an augmented internet-supported transdiagnostic intervention in Romania. 2. To assess the cost-effectiveness of the Internet version of the transdiagnostic program as compared to a standard treatment/usual care.

NCT ID: NCT02678624 Completed - Panic Disorder Clinical Trials

Project Collabri for Treatment of Anxiety

Start date: November 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether treatment of patients with anxiety according to the Collabri Model is more effective in reducing symptoms compared to treatment as usual (TAU)

NCT ID: NCT02631694 Not yet recruiting - Panic Disorder Clinical Trials

Disruption of Memory Reconsolidating as a Treatment for Panic Disorder

Start date: April 2016
Phase: Phase 2
Study type: Interventional

Animal and human fear conditioning studies have repeatedly shown that administering propranolol before or after retrieval of a previously acquired fear results in an elimination of the fear expression. This approach, known as disruption of fear memory reconsolidation, is a promising new avenue for treating anxiety disorders. The present study aims to test its efficacy in patients with panic disorder.

NCT ID: NCT02615119 Completed - Clinical trials for Major Depressive Disorder

Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa

Start date: October 1, 2015
Phase: N/A
Study type: Interventional

This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or brain injury. By evaluating the same interoceptive sensations across different human illnesses, the investigators hope to provide convergent evidence resulting in identification of core underlying neural processes, and to discern relative contributions in each condition.

NCT ID: NCT02605668 Completed - Panic Disorder Clinical Trials

Providing Tools for Effective Care and Treatment of Anxiety Disorders

PROTECT-AD
Start date: December 12, 2015
Phase: N/A
Study type: Interventional

PROTECT-AD is a cognitive behavioral treatment study involving highly qualified psychotherapeutic centers at seven German universities. It is our goal to further investigate and optimize existing effective treatments of anxiety disorders. In order to achieve this, the investigators want to investigate the effect of extinction learning in an "intensified" psychological intervention on treatment outcome in adults and children with anxiety disorders. The intensified psychological intervention is characterized by a higher number of exposure trials over a short time period. In the control condition the exposure trials take place in a weekly interval, analog to standard care.

NCT ID: NCT02593682 Completed - Panic Disorder Clinical Trials

The Role of Orexin in Human Panic Disorder

Start date: May 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to provide some information (pilot data) about whether the study drug, suvorexant, (1) affects levels of orexin in people with panic disorder, and (2) is associated with decreased panic symptoms in response to a carbon dioxide (CO2) challenge.

NCT ID: NCT02476136 Active, not recruiting - Anxiety Disorders Clinical Trials

Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis

Start date: May 2015
Phase: N/A
Study type: Observational

Anxiety disorders are common disorders, which pose a major burden to society and the individual. An anxiety disorder may be treated with medication, in particular with antidepressants such as the selective serotonin reuptake inhibitors (SSRIs). However, much of what is known about antidepressants is derived from research in depression rather than anxiety. In recent years, researchers have found that antidepressants are more effective for severely depressed patients than they are for patients with milder symptoms. It is possible that a similar relationship between symptom severity and antidepressant efficacy exists for anxiety disorders, but there is currently little evidence available to answer this question. As antidepressants are frequently prescribed to patients with mild or moderate anxiety, a clear understanding of their effectiveness across the severity range is vital to inform treatment decisions. Therefore, the purpose of this meta-analysis is to examine whether initial symptom severity affects antidepressant efficacy for anxiety disorders.

NCT ID: NCT02402322 Completed - Panic Disorder Clinical Trials

Internet-based Self-help Treatment for Panic Disorder: Two Ways of Complementary Psychological Support

Start date: August 2013
Phase: N/A
Study type: Interventional

The aim of this study was to compare two ways of administrating the complementary psychological support (scheduled vs. non-scheduled) in an online self-help program for panic disorder. In order to do so, the investigators studied: a) If there were differences in the intensity and frequency of the symptoms of panic disorder. b) If there were differences in the therapeutic adherence between the subjects receiving both kinds of complementary support. c) If the more time spent by a psychologist in therapeutic interventions produced the best results of therapeutic adherence / symptom improvement. Seventy seven subjects followed the online self-help program for 8 weeks; 27 subjects had the support of a therapist via phone when they required it, 25 subjects had the support of a therapist weekly and 25 subjects were in the waiting list as a control group.

NCT ID: NCT02395510 Completed - Panic Disorder Clinical Trials

A 10-Week, Open-Label, Flexible Dose Adaptive Study Evaluating the Efficacy of Vortioxetine in Subjects With Panic Disorder

Start date: May 2015
Phase: Phase 4
Study type: Interventional

The primary aim of this study is to evaluate the efficacy of Vortioxetine in an adult population with a diagnosis of PD. PD is generally treated with benzodiazepines which are very effective but have a high risk for addiction, fall, and cognitive impairment. There is still a need for better treatment for PD for longer term use. There are other drugs within the SSRI/SNRI class which have proven to be effective in treating patients with this diagnosis.