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Palliative Care clinical trials

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NCT ID: NCT00674609 Completed - Pain Clinical Trials

A Study of Sativex® for Pain Relief in Patients With Advanced Malignancy

SPRAY
Start date: February 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether Sativex® and GW-2000-02 are effective in the management of subjects with intractable cancer-related pain.

NCT ID: NCT00614003 Completed - Palliative Care Clinical Trials

Evaluation of an Intervention Designed to Enhance the Quality of Decision Support Provided to Patients Making Decisions About End-of-life Place of Care

Start date: April 2007
Phase: Phase 2
Study type: Interventional

Most dying cancer patients would prefer a home death yet die in an institution. Patients can experience uncertainty when weighing practical considerations, concern for others, and their personal ratings about the desirability and undesirability of various outcomes related to different locations of care. Health professionals, trained in decision support, can help patients to make decisions that are informed by both relevant information and what outcomes are most valued by patients. Therefore, I will study if an educational intervention can help nurses and case managers to strengthen their skills and confidence in providing patient decision support around place of end of life care. Project Description: Using a two step approach I will study if the quality of providers decision support can be improved with an education. In step one nurses and care coordinators will be interviewed to identify factors that make it easier or more difficult to provide patient decision support. This information will be used to develop an education program. In step two, nurses and care coordinator volunteers will be assigned by a flip of a coin to either receive the decision support education or not. Before and after the education program the quality of the decision support participants provide will be measured and compared. As well, participants receiving the education program will be asked about their satisfaction with the education program.

NCT ID: NCT00565188 Completed - Cancer Clinical Trials

Application of ATP Infusions in Palliative Home Care

Start date: March 2002
Phase: Phase 3
Study type: Interventional

Palliative care in cancer aims at alleviating the suffering of patients. A previous study in patients with advanced non-small-cell lung cancer showed that adenosine 5'-triphosphate (ATP) infusions had a favourable effect on fatigue, appetite, body weight, muscle strength, functional status, quality of life, and survival. Based on these promising results, the present study was designed 1. To evaluate whether the beneficial effects of ATP administration observed in patients with advanced lung cancer would also be present in pre-terminal cancer patients of different tumour types, and 2. To test the feasibility of application of ATP infusions in a home care setting.

NCT ID: NCT00545129 Completed - Neoplasm Metastasis Clinical Trials

A Study Of Tanezumab as Add-On Therapy to Opioid Medication In Patients With Pain Due To Cancer That Has Spread To Bone

Start date: April 29, 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the safety and efficacy of tanezumab in combination with opioids in treating pain due to cancer that has spread to bone.

NCT ID: NCT00530764 Completed - Pain Clinical Trials

A Study of Sativex® for Pain Relief in Patients With Advanced Malignancy.

SPRAY
Start date: November 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effective dose range and to demonstrate a non-effective dose range of Sativex in patients with advanced cancer, who experience inadequate pain relief even though they are on optimized chronic opioid therapy.

NCT ID: NCT00494910 Completed - Palliative Care Clinical Trials

Randomized Controlled Trial of Group Psychotherapy Interventions for Cancer Patients

Start date: June 26, 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare two types of group counseling for cancer patients: Meaning-Centered counseling and Supportive counseling. Many cancer patients seek counseling to help with the emotional burden of their illnesses. Counseling often helps them cope with cancer by giving them a place to express their feelings. "Meaning-Centered" group counseling is intended to teach cancer patients how to maintain or even increase a sense of meaning and purpose in their lives, despite cancer. "Supportive" group counseling is intended to help you cope with cancer by giving you a place to express your feelings and get support from other cancer patients. The purpose of this study is to compare the benefits of these two types of counseling approaches for cancer patients.

NCT ID: NCT00302185 Completed - Neoplasms Clinical Trials

Acupuncture in Palliative Cancer Care

Start date: June 2007
Phase: Phase 3
Study type: Interventional

Research question: Can acupuncture improve symptom control and quality of life (QOL) in patients with advanced incurable cancer? The purposes of this study is to investigate the feasibility of performing a randomized trial with acupuncture in improving symptom control and quality of life (QOL) in patients with advanced incurable cancer at the BC Cancer Agency, Vancouver Island Centre in Victoria. We will: - Evaluate whether subjects who are receiving palliative care for cancer related symptoms can tolerate and complete to a course of acupuncture treatments. - Evaluate whether it is possible to conduct a study using acupuncture on cancer patients.

NCT ID: NCT00271687 Completed - Prostatic Neoplasms Clinical Trials

A Pilot Study of Exercise in Patients With Docetaxel-Based Chemotherapy for Hormone Refractory Prostate Cancer

Start date: February 2006
Phase: Phase 2
Study type: Interventional

This study aims to provide preliminary data on the feasibility and outcomes of a 12 week exercise program on the quality of life of men with hormone refractory prostate cancer receiving docetaxel-based chemotherapy.

NCT ID: NCT00129467 Completed - Depression Clinical Trials

Methylphenidate for Depressed Cancer Patients Receiving Palliative Care

Start date: February 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether methylphenidate is an effective treatment for depression and to document the safety and tolerability of methylphenidate in combination with an Selective Serotonin Reuptake Inhibitor (SSRI) in SSRI treated, terminally ill, hospice and palliative care cancer patients. The investigators hypothesize that depressed hospice and palliative care patients will be more likely to have a 50% reduction in scores on a clinical measure of depression after treatment with Methylphenidate plus an SSRI compared to those patients who are taking a placebo plus an SSRI.

NCT ID: NCT00106041 Completed - Palliative Care Clinical Trials

Study to Improve Care for Veterans During Serious Illness

Start date: August 2004
Phase: N/A
Study type: Interventional

Improving end-of-life care is of critical importance to the VA as it faces an increasingly aging and dying veteran population. Previous work within and outside of the VA has demonstrated serious deficiencies in the quality of care delivered near the end of life. Moreover, veterans in the VA system suffer from a higher rate of chronic and life-limiting illnesses and decrements in health-related quality of life compared with the age-matched controls. In FY2000 approximately 104,000 enrolled veterans died in the U.S. including 27,200 that died as inpatients in VA acute or chronic care medical wards. The care model on which the proposed study is based is theoretically sound and has been piloted in a study that suggested its use can help the VA achieve substantial quality improvement at reduced costs.