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Pain clinical trials

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NCT ID: NCT02854553 Not yet recruiting - Pain Clinical Trials

TAP Block Alone Versus TAPblock With Rectus Sheath Block in Liposuction Surgery

Start date: September 2016
Phase: N/A
Study type: Interventional

The transversus abdominis plane (TAP) block is an effective regional nerve block for the anterior abdominal wall. An anesthesiologist typically administers the TAP block preoperatively with ultrasound guidance. It is not yet commonly used during anterior abdominal wall liposuction, where postprocedural pain remains a major concern for patients and surgeons.

NCT ID: NCT02840838 Not yet recruiting - Pain Clinical Trials

Botulinum Toxin for Post Abdominoplasty Pain Control

Start date: December 2018
Phase: Phase 4
Study type: Interventional

We are investigating ways to reduce pain after abdominoplasty. We hypothesize that injection of Dysport (botulinum toxin A) into the rectus abdominis, abdominal wall musculature, during abdominoplasty will provide a more effective, longer lasting method for pain control than standard of care alone (use of Exparel (liposomal bupivacaine) intraoperatively followed by PRN narcotics. We will randomize patients to receive either Disport + standard of care or saline (placebo) + standard of care and compare post operative pain for the following 2-3 months.

NCT ID: NCT02839928 Not yet recruiting - Pain Clinical Trials

Nasal Ketamine for Minor Procedures in Children

Start date: July 2016
Phase: N/A
Study type: Interventional

Nasal Ketamine has previously been tested in children for deep sedation or preoperative anxiolysis. The investigators intend to test the efficacy of low dose nasal Ketamine in children undergoing minor procedures in the emergency department.

NCT ID: NCT02826876 Not yet recruiting - Pain Clinical Trials

The Efficacy of Surgical Site Treatment With Ropivacaine in Laparoscopic Surgery

Start date: July 2016
Phase: N/A
Study type: Interventional

Using local analgesia in laparoscopic surgery in order to reduce pain and to reduce the use of narcotic drugs.

NCT ID: NCT02826109 Not yet recruiting - Pain Clinical Trials

The Efficacy of Cyanoacrylate Adhesive (PeriAcryl®90 HV) in Periodontal Wound Healing

Start date: June 2016
Phase: Phase 4
Study type: Interventional

Periodontal disease is a gum infection caused by plaque on teeth containing both bacteria and calculus (hard) deposits. These need to be removed on a regular basis to maintain gum health and to prevent teeth weakening. A routine cleaning procedure, scaling/root planing, is accompanied with post-operative soft tissue tenderness and teeth sensitivity making oral hygiene maintenance difficult during wound healing. The need for novel therapeutic approaches, such as cyanoacrylate adhesives, has been identified. It has been hypothesized that its application may provide comfort and assist patients with their daily oral self-care procedures following teeth cleaning.

NCT ID: NCT02823119 Not yet recruiting - Pain Clinical Trials

Mini-hysteroscopy Versus Conventional Office Hysteroscopy in Nulliparous Patients Undergoing Office Hysteroscopy

Start date: August 2016
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the effect of hysteroscope diameter on the pain experienced by nulliparous patients undergoing diagnostic office hysteroscopy.

NCT ID: NCT02801786 Not yet recruiting - Pain Clinical Trials

TAmoxifen Versus LIdocaine Cream. A Randomized Clinical Trial for Reducing Pain and Discomfort During Mammography

TALI
Start date: November 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This is a double-blind placebo-controlled randomized clinical trial to test the use of tamoxifen or lidocaine for diminishing the pain and discomfort while performing mammography, intending to include 450 patients distributed between the three groups.

NCT ID: NCT02784301 Not yet recruiting - Pain Clinical Trials

Evaluation of a Biofeedback Tool to Minimize Procedural Pain and Anxiety in Children

Start date: May 2016
Phase: N/A
Study type: Interventional

Belly breathing is a popular relaxation technique used to reduce anxiety and pain in children during medical procedures. The investigators have developed a biofeedback game that will help teach children how to belly breathe in an interactive way. Existing studies have shown that biofeedback tools are effective ways to teach relaxation techniques to children. The purpose of this study is to evaluate 1) whether this new biofeedback tool is a more a effective and engaging way to teach belly breathing to children and 2) whether the application is more effective in reducing procedural pain and anxiety compared to standard of care, self-directed belly breathing alone or self-directed belly-breathing combined with visual distraction. The investigators hypothesize that: 1. The smartphone-based biofeedback game for belly breathing will reduce self-reported procedural anxiety and pain in children during a blood collection procedure compared to: 1. standard of care 2. belly breathing + standard care procedures 3. belly breathing with visual components of the application with no coaching or biofeedback distraction. 2. The smartphone-based biofeedback game will increase compliance with belly breathing compared to self-directed breathing. 3. Belly breathing with smartphone-based biofeedback game will be more engaging compared to self-directed belly breathing.

NCT ID: NCT02618603 Not yet recruiting - Stroke Clinical Trials

Botulinum Toxin A for Shoulder Pain After Stroke

Start date: February 2016
Phase: Phase 4
Study type: Interventional

Shoulder pain after stroke is a very common, causing significant morbidity disease. Subacromial and subdeltoid (SASD) bursitis are common causes of pain or disability of the shoulder joint in stroke patients. Traditional therapeutic approaches for the shoulder pain therapy including pharmacotherapy, injection therapy, physical therapy, and behavioural modification. Unfortunately, these therapy methods may not be effective in many patients and long term benefit after treatment is transient, the outcomes may also be incomplete or non-existent. Botulinum toxin A (BoNT-A) is a neurotoxin that can inhibit not only the acetylcholine at the neuromuscular junctions but also other neurotransmitters such as glutamate, substance P and calcitonin gene related peptide, all of which have been indicated in pain transmission. Despite the therapeutic benefit of BTX in alleviating painful muscle spasms, its efficacy in SASD bursitis conditions is less clear. So we perform this study to examine the efficacy of ultrasound guided SASD injection with BoNT-A in reducing refractory shoulder pain after stroke.

NCT ID: NCT02611726 Not yet recruiting - Pain Clinical Trials

Acupuncture for Symptom Control During Assisted Reproductive Treatments Procedures

Start date: December 2015
Phase: Phase 3
Study type: Interventional

Rationale for conducting the experiment: Israel performed IVF treatments since 1980. Although ART (Advanced Reproductive Treatments) have evolved over the years implantation and pregnancy rates have not met the expectations yet. Success rates of fertility treatments are about 15-18% (clinical pregnancy rates =CPR). As a result additional methods (clinical, technological and complimentary) have been tried to improve the CPR. In some reviews the effects of acupuncture practice during fertility treatments showed certain benefits, including pain relief and relaxation. Unfortunately those trials were not randomized and lacked methodological rigor. The aim of this study is to evaluate the effect of acupuncture on pain, anxiety, and CPR of women undergoing IVF as compared to standard care alone.