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Clinical Trial Summary

The main aim is to determine whether vitamin C can reduce 28-day all-cause mortality or persistent organ dysfunction compared with placebo in patients with severe and critical ill COVID-19 patients. Participants will randomly receive HIVC or placebo for 4 days once enrolled. The primary outcome is a composite of death or persistent organ dysfunction (defined as dependency on vasopressors, mechanical ventilation, or CRRT) at day 28 after randomization.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05694975
Study type Interventional
Source Zhujiang Hospital
Contact Liu Zhanguo, MD,PhD
Phone 18520711669
Email zhguoliu@163.com
Status Recruiting
Phase Phase 2/Phase 3
Start date January 13, 2023
Completion date June 2023

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