Prevalence and Associated Factors of Functional Gastrointestinal Disorders Among Children

Functional Gastrointestinal Disorders Clinical Trial

Official title:

Prevalence and Associated Factors of Functional Gastrointestinal Disorders Among Children Attending Assuit University Children Hospital

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05605405
• Other study ID #: PAAFOFGDACAAUCH
• Status: Not yet recruiting
• Start date: December 2022
• Est. completion date: December 2023

Study information

• Verified date: October 2022
• Source: Assiut University
• Contact: Dalia Galal Mahran, MD
• Phone: 01007120821
• Email: Daliaym2001[@]yahoo.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The definition of Functional Gastrointestinal Disorders (FGIDs) has changed over time from the absence of organic disease to a stress-related or psychiatric disorder to a motility disorder, and with Rome III, to a disorder of GI functioning, then Rome iv in 2016 defined FGIDs as : disorders of gut-brain interaction. It is a group of disorders classified by GI symptoms related to any combination of the following: motility disturbance, visceral hypersensitivity,altered mucosal and immune function, altered gut microbiota, and altered central nervous system (CNS) processing. FGIDs are observed in infants and young children worldwide with variable frequency related studies done in variable places around the worled show the following results : the prevalence of FGIDs in Chinese infants and young children is 27.3%.and 40 % in south american infants and 30 % of african infants and 35.1 % of infants presented to tertiary care hospital in Istunbul.Turkey.

Description:

The etiology of these disorders remains uncertain and thought to be due to subtle alteration of the normal development or maladaptive behavioral response to a variety of internal or external stimuli .As a group of disorders; FGIDs in young children are a major challenge to the already overstretched pediatric gastroenterology services across the world .Infants and young children with FGIDs visit medical professionals more frequently and experience poor quality of life . In addition, FGIDs in infancy are linked with detrimental repercussions such as maternal depression, poor infant and mother bonding,and poor physical growth .

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 269
• Est. completion date: December 2023
• Est. primary completion date: September 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 1 Year to 18 Years

Eligibility

Inclusion Criteria:

• Age group 1 to 18 years old

Exclusion Criteria:

• Age group bwlow 1 year and above 18 years

Having other git problem as :

• GIT bleeding

• H pylori infection

• Cow's milk protein allergy or IBD or any other symptoms suggestive to organic GI disease

Related Conditions & MeSH terms

• Digestive System Diseases
• Functional Gastrointestinal Disorders
• Gastrointestinal Diseases

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of functional gastrointestinal disorders among children attending gastrointerology clinic of Assuit University Children Hospital	A number will calculated	50 weeks
Primary	The associated factors	Demographic and social	50 weeks