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Clinical Trial Summary

This is a Phase I, open-label, dose escalation study of LNP3794 (BI3011441) in subjects with NRAS/KRAS mutated advanced or metastatic refractory solid tumors. The purpose of this study is to evaluate the safety/tolerability, pharmacokinetic and pharmacodynamic profile of the orally administered LNP3794 (BI3011441) as monotherapy at selected dose levels.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05187858
Study type Interventional
Source Lupin Ltd.
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Status Active, not recruiting
Phase Phase 1
Start date September 22, 2020
Completion date May 10, 2022