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Clinical Trial Summary

The prevalence of lower extremity arterial disease (LEAD) in patients with diabetes increases significantly and are characterized with obvious arteriosclerosis that are caused by multiple metabolic disorders. Metabolomics measures the metabolites in biological fluids or tissues that generated under certain conditions via rapidly evolving high-throughput technology. Herein, the investigators designed the study to characterize the serum metabolic profiles of LEAD patients and identify metabolic biomarkers using metabolomics. The serum of volunteers, type 2 diabetes mellitus(T2DM) patients with or without LEAD were collected and analyzed using liquid chromatography-mass spectrometry(LC-MS) coupled with a series of multivariate statistical analyses.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05068895
Study type Observational
Source Third Military Medical University
Contact
Status Recruiting
Phase
Start date June 1, 2021
Completion date October 15, 2021

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