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Clinical Trial Summary

assess electrophysiological changes in some facial muscle dynamics following hyaluronic acid filler injection in superficial versus deep level of injection.


Clinical Trial Description

Participants will be subjected to injection of cross-linked hyaluronic acid fillers on both sides of the face in 3 different regions: temples, cheeks and chins. Each female will undergo: 1. Before injection: 1. Aesthetic facial clinical analysis. 2. Baseline quantitative surface electromyography. 3. Baseline digital photography. 2. Injection: Each female will receive the injection in the particular facial region at superficial level to the muscle (subcutaneous) on one side and the same amount at deep level to the muscle (supraperiosteal) on the other side. 3. One week after injection: 1. Follow up quantitative surface electromyography. 2. Follow up digital photography. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05034965
Study type Interventional
Source Alexandria University
Contact Marwa Eldeeb
Phone +201200029774
Email [email protected]
Status Recruiting
Phase Early Phase 1
Start date October 2021
Completion date October 2022