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Clinical Trial Summary

The purpose of this study is to evaluate the efficacy and safety of two different doses of MK-2060 (a monoclonal antibody against Factor XI) in end stage renal disease (ESRD) participants receiving hemodialysis via an arteriovenous graft (AVG). Data from this study will be used to aid dose selection of MK-2060 in future studies. The primary hypothesis is that at least one of the MK-2060 doses is superior to placebo in increasing the time to first occurrence of AVG event.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05027074
Study type Interventional
Source Merck Sharp & Dohme Corp.
Contact
Status Not yet recruiting
Phase Phase 2
Start date September 27, 2021
Completion date April 18, 2023

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