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Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study

Chronic Graft Versus Host Disease Clinical Trial

Official title:
Predicting the Quality of Response to Specific Treatments (PQRST)

Clinical Trial Summary

This trial collects clinical data and blood samples to predict the quality of response to specific treatments in patients with chronic graft-versus-host disease (cGVHD) who are about to start initial or second-line therapy. Collecting and analyzing clinical data and blood samples from patients with cGVHD before and after treatment initiation may help doctors identify changes that may predict treatment response.

Clinical Trial Description

OUTLINE: Patients complete questionnaires over 10 minutes about physical symptoms, activity level, and emotional well-being and have their medical records reviewed at baseline, 1, 3, and 6 months after starting index treatment, and at start of a new systemic treatment. Patients also undergo collection of blood samples over 1-2 minutes at baseline and at 1 month after starting index treatment, or at a treatment change visit if new therapy has not started. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04431479
Study type Observational
Source Fred Hutchinson Cancer Center
Contact Stephanie J Lee
Phone 206-667-6190
Email sjlee@fredhutch.org
Status Recruiting
Phase
Start date June 29, 2020
Completion date August 2, 2025
View Details
See also
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