Other Clinical Trial - DOAC ADRs Retrospective Study

Status Terminated

Clinical Trial Summary

This retrospective study's objective is to evaluate if Cipherome's algorithm could have predicted the serious adverse drug reactions (ADRs) experienced by patients while on direct oral anti-coagulants (DOACs).

Clinical Trial Description

Using the latest next generation sequencing tools, this study will evaluate adverse drug reactions (ADRs) (e.g., major bleeding or treatment failure) in study participants while on direct oral anticoagulants (DOACs). A web-based program will analyze the data obtain from sequencing, and generate a drug safety score (DSS). The DSS risk score will be compared with pre-specified serious ADRs associated with DOAC therapy. A secondary analysis will involve discovery of novel variants that arise from our analysis and may potentially affect the outcome of DOAC treatment. ;

Study Design

Related Conditions & MeSH terms

Drug-Related Side Effects and Adverse Reactions

Clinical Trial Details

NCT number	NCT04247919
Study type	Observational
Source	Cipherome, Inc.
Contact
Status	Terminated
Phase
Start date	January 10, 2020
Completion date	July 24, 2020

View Details

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