Exudative Age-related Macular Degeneration Clinical Trial
Official title:
Study of Retinal and Vascular Features by Optical Coherence Tomography and Optical Coherence Tomography Angiography After Intravitreal Injections of Bevacizumab in Exudative Age-related Macular Degeneration
This study evaluates the retinal and vascular features in patients with macular degeneration under the effects of Bevacizumab intravitreal injections using optical coherence tomography and optical coherence tomography angiography.
Bevacizumab is a vascular endothelial growth factor antagonist represent an efficacy
treatment for exudative age-related macular degeneration acting on vascular
hyperpermeability.
The optical coherence tomography and optical coherence tomography angiography represent novel
and non-invasive diagnostic techniques that allow a detailed and quantitative analysis of
retinal and vascular features.
The study evaluates the changes in optical coherence tomography and optical coherence
tomography angiography parameters at baseline and after three monthly injections of
Bevacizumab in exudative AMD.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT01950741 -
Effect of Intravitreal VEGF-Trap Eye on Polypoidal Choroidal Vasculopathy
|
Phase 4 | |
| Recruiting |
NCT01608113 -
Long-term Follow-up of Subfoveal Neovascular AMD
|
N/A | |
| Completed |
NCT01404845 -
Macular Pigment Density Evolution in Unilateral Wet AMD Versus Non AMD Patients With or Without Lutein and Zeaxanthine Supplementation
|
N/A | |
| Completed |
NCT01213082 -
ProspectiveTrial of Proton Beam Combined With Anti-VEGF Therapy for Exudative Age-related Macular Degeneration (AMD)
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT01961414 -
Treat and Extend Therapy Study Using Intravitreal Aflibercept for Patients Exited From Protocol VGFT-OD 0910
|
Phase 4 | |
| Completed |
NCT01304693 -
ESBA1008 Safety, Tolerability and Effects in Wet Age-Related Macular Degeneration (AMD) Patients
|
Phase 1/Phase 2 | |
| Completed |
NCT01810042 -
Indocyanine Angiographic Changes of Choroidal Neovascularization by Ranibizumab
|
Phase 4 | |
| Completed |
NCT04640272 -
A Multi-Center, Open Label, Extension Study Assessing the Efficacy and Safety of Additional Intravitreal Injections of RBM-007 in Subjects With Wet Age-related Macular Degeneration
|
Phase 2 | |
| Active, not recruiting |
NCT02976194 -
Intraocular Cytokine in Recurrence of Polypoidal Choroidal Vasculopathy
|
Phase 4 | |
| Completed |
NCT01500915 -
FUSION Regimen: Combined Pro re Nata and Fixed Regimen Ranibizumab in Exudative Age-related Macular Degeneration
|
Phase 4 | |
| Enrolling by invitation |
NCT05539235 -
Efficacy and Safety of Intravitreal Conbercept With Modified Treat-and-Extend Regimens in Exudative AMD
|
Phase 2/Phase 3 | |
| Completed |
NCT02355028 -
LHA510 Proof-of-Concept Study as a Maintenance Therapy for Patients With Wet Age-Related Macular Degeneration
|
Phase 2 | |
| Unknown status |
NCT02089503 -
Monocentric Retrospective Observational Study on Patients With Macular Degeneration
|
N/A | |
| Completed |
NCT01796964 -
Efficacy and Safety Study of ESBA1008 Versus EYLEA®
|
Phase 2 | |
| Completed |
NCT01127360 -
LUCAS (Lucentis Compared to Avastin Study)
|
Phase 4 | |
| Terminated |
NCT02348359 -
X-82 to Treat Age-related Macular Degeneration
|
Phase 2 | |
| Recruiting |
NCT02328209 -
Evaluation of the Simplified Treat And Extend Regimen Using Ranibizumab in Exudative Age Related Macular Degeneration
|
N/A | |
| Completed |
NCT01849692 -
ESBA1008 Microvolume Study
|
Phase 2 | |
| Completed |
NCT01157065 -
Evaluation of AL-78898A in Exudative Age-Related Macular Degeneration
|
Phase 2 | |
| Completed |
NCT03744806 -
Blood-aqueous Barrier Integrity in Eyes Undergoing Intravitreal Bevacizumab Therapy to Treat Neovascular AMD
|