Peripheral Perfusion Index (PPI) as Monitor During Deliberate Hypotensive Anesthesia

Monitoring During Deliberate Hypotensive Anesthesia Clinical Trial

— PPI  

Official title:

The Use of Peripheral Perfusion Index as a Predictor for Patient's Response to Deliberate Hypotension During Functional Endoscopic Sinus Surgery A Prospective Observational Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03007355
• Other study ID #: N 2015
• Status: Completed
• Start date: January 2017
• Est. completion date: December 2017

Study information

• Verified date: December 2018
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue. Peripheral Perfusion Index (PPI) as a noninvasive new monitoring, can reflect the peripheral perfusion dynamics.

This study is designed to explore the behaviour and trend of PPI during nitroglycerine induced deliberate hypotensive anesthesia in adult patients undergoing functional endoscopic sinus surgery (FESS).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 50
• Est. completion date: December 2017
• Est. primary completion date: October 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Patients, aged from 18-50 years, ASA physical status I and II, undergoing functional endoscopic sinus surgery (FESS) under deliberate hypotensive anesthesia

Exclusion Criteria:

• Patients with systemic hypertension, cardiovascular disease, cerebrovascular insufficiency, coagulation defects, renal or hepatic insufficiency, and hypersensitivity to the study drugs will be excluded from the study. Patients receiving vasoactive drugs or beta blockers will be also excluded from the study.

Related Conditions & MeSH terms

• Monitoring During Deliberate Hypotensive Anesthesia

Intervention

Other:
• peripheral perfusion index measurement

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	correlation between PPI and T1	correlation of baseline values of PPI and time required to achieve target mean arterial pressure.	start of nitroglyceirn infusion till target arterial pressure is reached up to 2 hours