Osteoporosis Clinical Trial
Official title:
Calcitonin Receptor Gene Polymorphisms in Patients With Osteoporosis and Chronic Periodontitis-An Observational Study
Osteoporosis and Periodontitis are multifactorial diseases which share common risk factors.The aim of the present study is to ellucidate polymorphisms in Calcitonin receptor gene? in patients with Osteoporosis and Periodontitis.
Periodontitis is a polymicrobial inflammatory disease which includes various modifiable and
nonmodifiable risk factors. The non modifiable risk factors include genetic polymorphisms
like metabolism associated genetic polymorphisms ( Vitamin D and Calcitonin).
Osteoporosis is a systemic skeletal disease characterized by low bone mass and
micro-architectural deterioration of bone tissue with consequent increase in bone fragility
and susceptibility to fractures.
Bone loss is a common feature shared between periodontal disease and osteoporosis.
Out of all genetic factors Calcitonin gene polymorphism contributes to the development of
both osteoporosis and chronic periodontitis.
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Observational Model: Case Control, Time Perspective: Retrospective
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