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NCT01946451 Clinical Trial

Gene Expression in Patients With Epiretinal Membranes

Proliferative Diabetic Retinopathy Clinical Trial

Official title:
Gene Expression and Their Correlations in Patients With Idiopathic and Secondary Epiretinal Membranes in Proliferative Diabetic Retinopathy

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT01946451
Other study ID # SilesianMU
Secondary ID
Status Active, not recruiting
Phase N/A
First received September 16, 2013
Last updated September 18, 2013
Start date June 2012
Est. completion date December 2013

Study information
Verified date September 2013
Source Medical University of Silesia
Contact n/a
Is FDA regulated No
Health authority Poland: Ethics Committee
Study type Observational

Clinical Trial Summary

The purpose of this study was to investigate the expression of selected genes both in epiretinal membranes (ERMs) and peripheral blood mononuclear cells (PBMCs) from patients with primary and secondary epiretinal membranes in proliferative diabetic retinopathy. Possible correlations between messenger ribonucleic acid (mRNA) levels of these genes were also identified.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 0
Est. completion date December 2013
Est. primary completion date September 2013
Accepts healthy volunteers No
Gender Both
Age group 55 Years and older
Eligibility Inclusion Criteria:

- Caucasian race,

- both males and females,

- aged = 55 years,

- suffering from idiopathic ERMs or secondary ERMs in proliferative diabetic retinopathy (PDR).

- Presence of ERM was proven in optical coherence tomography (OCT) examination.

Exclusion criteria:

- aged < 55 years,

- systemic connective tissue disease,

- active inflammatory process

Study Design

Observational Model: Case Control, Time Perspective: Retrospective

Related Conditions & MeSH terms

Locations
Country Name City State
Poland Medical University of Silesia Katowice

Sponsors (1)
Lead Sponsor Collaborator
Medical University of Silesia

Country where clinical trial is conducted

Poland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Gene expression in patients with idiopathic and secondary epiretinal membranes in proliferative diabetic retinopathy. The period between the diagnosis of the ERMs and the actual surgery for the condition was between 2 and 43 months. No
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