Losartan + Sunitinib in Treatment of Osteosarcoma

Status Recruiting

Clinical Trial Summary

This study is a Phase 1/1b clinical trial that aims to determine the Maximally Tolerated Dose of Losartan and Sunitinib Combination Therapy. Patients will first be accrued to the Dose Escalation phase of the study, using a 3+3 design. Medication dosages will increase until a maximally tolerated dose is found. Patients will then be accrued to the Dose Expansion phase of the trial, where efficacy of pre-determined dose will be preliminarily assessed.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Osteosarcoma

Clinical Trial Details

NCT number	NCT03900793
Study type	Interventional
Source	University of Colorado, Denver
Contact	Natalie Frisbie
Phone	720-848-0734
Email	natalie.frisbie@cuanschuz.edu
Status	Recruiting
Phase	Phase 1
Start date	August 26, 2019
Completion date	February 2027

View Details

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