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Open-Angle Glaucoma clinical trials

View clinical trials related to Open-Angle Glaucoma.

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NCT ID: NCT01342094 Completed - Ocular Hypertension Clinical Trials

DE-111 Against Timolol Ophthalmic Solution 0.5%

Start date: May 2011
Phase: Phase 3
Study type: Interventional

DE-111 ophthalmic solution will be evaluated for superiority in comparison with Timolol ophthalmic solution 0.5%, in IOP(intraocular pressure ) -lowering effect in primary open-angle glaucoma or ocular hypertension patients, in a multicenter, randomized, double-masked, parallel-group comparison study. Safety will be compared and evaluated as well.

NCT ID: NCT01342081 Completed - Ocular Hypertension Clinical Trials

DE-111 Against Tafluprost Ophthalmic Solution 0.0015% Alone and Concomitant Use of Tafluprost Ophthalmic Solution 0.0015% Plus Timolol Ophthalmic Solution 0.5%

Start date: May 2011
Phase: Phase 3
Study type: Interventional

DE-111 ophthalmic solution will be evaluated for superiority in comparison with Tafluprost 0.0015% ophthalmic solution, or for non-inferiority in comparison with Tafluprost 0.0015% and Timolol ophthalmic solution 0.5% used concomitantly, in IOP(intraocular pressure) -lowering effect in primary open-angle glaucoma or ocular hypertension patients, in a multicenter, randomized, double-masked, parallel-group comparison study. Safety will be compared and evaluated as well.

NCT ID: NCT01340014 Completed - Ocular Hypertension Clinical Trials

Patient Preference Comparison of AZARGA Versus COSOPT

Start date: September 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study was to assess patient preference regarding ocular comfort of AZARGA® compared to COSOPT® after one week instillation of each study medication.

NCT ID: NCT01330979 Completed - Ocular Hypertension Clinical Trials

24-hour Efficacy of AR-12286

Start date: May 2011
Phase: Phase 2
Study type: Interventional

An open-label, non-comparative, pilot evaluation of the 24-hour ocular hypotensive efficacy of AR-12286 in patients with open-angle glaucoma or ocular hypertension

NCT ID: NCT01327599 Completed - Ocular Hypertension Clinical Trials

Efficacy of Changing to DUOTRAV® From Prior Therapy

Start date: August 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study was to assess the efficacy and tolerability of changing to DUOTRAV® from prior bimatoprost 0.03%/timolol 0.5% pharmacotherapy in subjects with open-angle glaucoma or ocular hypertension having uncontrolled intraocular pressure (IOP).

NCT ID: NCT01310777 Completed - Ocular Hypertension Clinical Trials

Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension

Start date: May 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety and efficacy of Brinzolamide/Brimonidine in lowering intraocular pressure (IOP) relative to each of its individual active components in patients with open-angle glaucoma or ocular hypertension.

NCT ID: NCT01309204 Completed - Ocular Hypertension Clinical Trials

Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension

Start date: May 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety and efficacy of Brinzolamide/Brimonidine fixed combination in lowering intraocular pressure (IOP) relative to each of its individual active constituents instilled concomitantly (Brinzolamide+Brimonidine) in patients with open-angle glaucoma or ocular hypertension.

NCT ID: NCT01306461 Completed - Ocular Hypertension Clinical Trials

Tafluprost-Timolol Fixed Dose Combination Non-Inferiority Study Against Concomitant Administrations

Start date: March 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of the preservative-free fixed-dose combination of tafluprost and timolol (FDC) to concomitant administration of tafluprost and timolol. This study will enroll patients who have ocular hypertension or glaucoma. The study schedule includes seven visits to the study site and three stages: - washout of 5 days to 4 weeks depending on current glaucoma medication (if any) - 6-month study treatment period - 1-3 weeks post-study period

NCT ID: NCT01304264 Completed - Open Angle Glaucoma Clinical Trials

Intraocular Pressure, Blood Pressure, Ocular Perfusion and Blood Flow Fluctuations in Glaucoma Patients

Start date: March 2011
Phase: N/A
Study type: Observational

To evaluate whether add-on to prostaglandin therapy with twice a day (bid) dorzolamide is statistically superior to twice a day (bid) timolol with regard to increasing ocular blood flow

NCT ID: NCT01298687 Completed - Ocular Hypertension Clinical Trials

Divided Dose of TRAVATAN®

Start date: February 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the incremental dosing of travoprost ophthalmic solution versus once a day dosing of TRAVATAN® in lowering intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT).