Obsessive-Compulsive Disorder Clinical Trial
Official title:
Transcranial Direct Current Stimulation as an add-on Treatment in SSRI-resistant Obsessive Compulsive Disorder : a Randomized Clinical Trial
The purpose of this study is to determine whether tDCS is effective as an add-on treatment in SSRI-resistant patients with obsessive and compulsive disorder
Total number of scheduled patients to be recruited: 46 We used the effect size of the study
of Ruffini and colleagues (2009) in which rTMS was used to target the left orbito frontal
cortex to calculate the number of patients to be recruited. With a risk alpha of 5%, a power
of 80%, the number of patients to be included was 46 with an anticipated rate of 10% of lost
to follow-up patients. (calculation was made on the
http://www.spc.univ-lyon1.fr/mfcalc/NSN/assistant.htm)
Statistical analysis to address the primary and secondary objectives:
Chi squared test will be applied for quantitative data.
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