Sarcopenia, Obesity, and Resistance Training

Obesity Clinical Trial

Official title:

Effects of Resistance Training on Sarcopenic Obesity Index in Older Women: a RCT.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02681744
• Other study ID #: 487622/2012-0
• Status: Recruiting
• Phase: N/A
• First received: February 10, 2016
• Last updated: February 11, 2016
• Start date: February 2016
• Est. completion date: August 2016

Study information

• Verified date: February 2016
• Source: University of Brasilia
• Contact: Ricardo M Lima, PhD
• Phone: +556184908490
• Email: gefsunb[@]gmail.com
• Is FDA regulated: No
• Health authority: Brazil: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

The purpose of this study was to examine the effects of resistance training on sarcopenic obesity in older women.

Description:

To examine the effects of resistance training on sarcopenic obesity in older women, a representative sample of older women from Brasília, Brazil (n>244 subjects), will be recruited and invited to undergo body composition measurement using dual-energy x-ray absorptiometry. Moreover, the Sarcopenic Obesity index and isokinetic strength evaluations will be performed. It will be a single-blind randomized, controlled 24-week clinical trial, in which experimental group will receive a progressive resistance training program, meanwhile control group will receive instructions to maintain their lifestyle habits. Randomization will be conducted by computer-generated list in blocks of 10. Additionally, body composition, strength assessment, and sarcopenic index will collected and compared after the intervention period.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 244
• Est. completion date: August 2016
• Est. primary completion date: August 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 60 Years to 80 Years

Eligibility

Inclusion Criteria:

• Community older women (aged between 60 and 80 years).

Exclusion Criteria:

• individuals with any metallic implant or artificial pacemaker, who had undergone hip surgery, who were unable to walk without assistance and those affected by metabolic or endocrine disorders that affect the muscular system.

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

• Aging
• Obesity
• Sarcopenia

Intervention

Behavioral:
• Resistance Training
24-weeks of progressive strength training

Locations

Country	Name	City	State
Brazil	Faculdade de Educação Física	Brasília	Distrito Federal

Sponsors (1)

Lead Sponsor	Collaborator
University of Brasilia

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Laboratorial Body Composition assessment (DXA)	DXA-derived body fat and DXA-derived fat free mass	30 minutes	Yes
Secondary	Isokinetic peak torque of leg extension (dynamometer isokinetic)	Dominant leg extension peak torque will be recorded in three sets of maximal effort	20 minutes	Yes