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Muscle Weakness clinical trials

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NCT ID: NCT04345224 Completed - Muscle Weakness Clinical Trials

The Effect of Dynamic and Rigid Tape Application on the Asymmetry of the Lower Limbs

Start date: December 10, 2020
Phase: N/A
Study type: Interventional

This is a prospective randomized three brachial, single-blinded, placebo-controlled trial, which aims at assessing the impact of the gluteal muscle taping with a dynamic tape and a non-elastic tape on the activation of the gluteal muscles and the distribution of the lower limb load in healthy people. The study participants will be randomly classified into the following groups: A - dynamic kinesiology taping, B - rigid tape, C - placebo group (sham). Patients will be evaluated three times - before applying the tapes, 30 minutes after applying the tapes and 48 hours after applying the tapes.

NCT ID: NCT04343599 Completed - Muscle Weakness Clinical Trials

Hypopressive Effectiveness in Postural Control and Pelvic Floor.

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

Effects of an exercise program based on hypopressive exercises in the female population.

NCT ID: NCT04302103 Completed - Clinical trials for Systemic Myasthenia Gravis

A Study of TACI(Transmembrane Activator and Calcium-modulator and Cyclophilin Ligand (CAML) Interactor)-Antibody Fusion Protein Injection (RC18) in Subjects With Systemic Myasthenia Gravis

Start date: July 7, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to initially observe the safety and effectivity of RC18 in Participants with systemic myasthenia gravis.

NCT ID: NCT04297111 Completed - Muscle Weakness Clinical Trials

Probiotic-Muscle Study

Start date: November 25, 2019
Phase: N/A
Study type: Interventional

This study will examine the effect of probiotic supplementation (Bacillus coagulans) on muscle protein synthesis in older adults in response to a plant-based diet. The investigators hypothesize that probiotic supplementation will enhance the digestibility of plant protein, therefore increasing the proportion of ingested amino acids that appear in systemic circulation and enhancing rates of muscle protein synthesis.

NCT ID: NCT04284748 Completed - Muscle Weakness Clinical Trials

Effect of Blood Flow Restriction Training on Patient With Anterior Cruciate Ligament Reconstruction

Start date: December 10, 2018
Phase: N/A
Study type: Interventional

This study investigates the effects of plyometric training with blood flow restriction on muscular strength, quadriceps thickness and knee joint function in patients with muscle weakness and atrophy (quadriceps muscle and hamstring muscle) after anterior cruciate ligament reconstruction. Persons who completed a 12-week routine rehabilitation program after anterior cruciate ligament reconstruction will be included in the study. In the study group, plyometric exercises will be performed with blood flow restriction in the operated side for 8 weeks. In the control group, the same plyometric exercises will be performed without any application.

NCT ID: NCT04284475 Completed - Critical Illness Clinical Trials

Relationship Between Muscle Strength and Physical Function in ICU

Start date: October 1, 2018
Phase:
Study type: Observational

This observational study aims to assess the relationship between muscle strength and physical function in critical ill patients. Grip and quadriceps strengths are measured using a standardized protocol of dynamometry. Physical function is assessed using the validated ICU mobility scale.

NCT ID: NCT04261452 Completed - COPD Clinical Trials

Heart Failure Worsens Muscle Strength in COPD

Start date: August 1, 2014
Phase: N/A
Study type: Interventional

The combination of heart failure (HF) and chronic obstructive pulmonary disease (COPD) is highly prevalent, but underdiagnosed and poorly recognized. It has been suggested that the decline in functional capacity is associated with musculoskeletal and systemic changes than primary organ (heart and/or lung) failure. In addition, it is recognized that both diseases have several mechanisms that are responsible for musculoskeletal impairment. However, the association of reduced systemic perfusion with low oxygen content observed in the association of HF and COPD may contribute to the worsening of the components of the muscle impairment cascade. Thus, muscle strength and fatigue may not only be even more altered but may also be the main determinants of functional capacity in patients with coexistence of HF and COPD. Although many studies have evaluated the muscle performance of patients with HF or COPD, the literature did not show data on worsening due to the association of the diseases. Particularities identification of the muscle impairment in the coexistence of HF and COPD is fundamental for the development of rehabilitation strategies, mainly through physical exercise. In this line, the present study tested the hypothesis that the coexistence of HF and COPD could present lower values of strength and greater fatigue. Similarly, the muscle dysfunction degree could strongly correlate with the performance markers of the incremental or functional tests in patients with HF associated with COPD. The study protocol was reviewed and approved by the Institutional Research Board. All subjects gave written informed consent before participating in the study.

NCT ID: NCT04207359 Completed - Breast Cancer Clinical Trials

Effects of Creatine Supplementation in Breast Cancer Survivors

Start date: September 30, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to test the hypothesis that creatine will accelerate adaptations associated with exercise in breast cancer survivors recently completing chemotherapy.

NCT ID: NCT04181671 Completed - Clinical trials for Muscle Weakness Condition

Low Resistance Venous Blood Flow Restriction Training (LR-VBFRT) on Biceps Brachii Muscle Performance

Start date: November 4, 2019
Phase: N/A
Study type: Interventional

Resistance training has been widely recognized as an effective stimulus for increasing skeletal muscle size and strength. This study intends to compare the effects of high resistance training without blood flow restriction and the low resistance training with blood flow restriction training on bicep muscle performance.

NCT ID: NCT04176211 Completed - Myasthenia Gravis Clinical Trials

The Impact of Myasthenia Gravis in the Real World

Start date: December 12, 2019
Phase:
Study type: Observational [Patient Registry]

An international, non-interventional, prospective, community recruited, longitudinal, lifestyle study which aims to collect Real-World Evidence (RWE) from people living with myasthenia gravis (MG) in order to map the disease's natural history, its burden on patients and their families, its treatment, as well as its medical, social and pharmacoeconomic impact.